This content is machine translated A hub of biological aging Mitochondrial dysfunction and energy metabolism Mitochondrial dysfunction is not defined as an isolated “ATP problem” in the Hallmarks of Ageing framework, but as a systemic shift in bioenergetics, redox signaling, quality control and immune metabolism....…
View Post 3 min This content is machine translated Health Literacy Promoting health literacy: from the abstract to the concrete level The Federal Council’s health policy strategy “Health 2030” sets out a framework for action in health policy aimed at securing healthcare provision in the coming years. The second of the...…
View Post 4 min This content is machine translated Case study Wiedemann-Steiner syndrome in a 2-year-old girl The patient, who had a phenotype characterized by hypertelorism, thick eyebrows and other features, was found to have a c.517C>T nonsense mutation in the KMT2A gene. This rare heterozygous mutation...…
View Post 4 min This content is machine translated Chronic back pain Care in the virtual hospital – the Back@home project As part of the Back@Home study, the effectiveness of a virtual hospital model is being evaluated in patients with musculoskeletal back pain who present to the emergency room. One of...…
View Post 5 min This content is machine translated Study report: TBS v3 and v4 in comparison Analysis of OsteoLaus study data The OsteoLaus study is part of the prospective, population-based CoLaus/PsyColaus study of postmenopausal women in Switzerland. In an analysis published in Osteoporosis International in 2025, the Trabecular Bone Score (TBS)...…
View Post 8 min This content is machine translated Psychooncology Communication as the key to therapy adherence Patient satisfaction and adherence depend crucially on the doctor-patient discussion. Communication skills are usually the key to success here. Good interview conditions, sufficient time and an empathetic approach to the...… CME-Test
View Post 5 min This content is machine translated How do weight loss interventions affect the muscles? Reflective evaluation: do not neglect qualitative aspects Both in the context of exclusively dietary interventions and after bariatric surgery or treatment with GLP(glucagon-like peptide)-1 analogs, there is not only a reduction in weight, but also a loss...…
View Post 7 min This content is machine translated From biomarkers to gene therapies Getting to know ataxias New developments in imaging, digital biomarkers and gene therapy are significantly changing the diagnosis and treatment of ataxia. Experts emphasize the clinically central distinction between sensitive and cerebellar ataxia, the...…
View Post 6 min This content is machine translated Obesity in the family practice Aim for realistic goals and avoid apportioning blame Morbid obesity is a significant health risk factor and its prevalence has increased in many industrialized countries in recent years. The principles of weight reduction have hardly changed over the...…
View Post 5 min This content is machine translated Early rheumatoid arthritis C1M has potential as a biomarker The earlier rheumatoid arthritis (RA) is diagnosed, the better the prognosis. But easier said than done. Conventional clinical, serological and imaging markers often lack sufficient sensitivity in the early stages...…
View Post 5 min This content is machine translated Osteoporosis Risk-stratified therapy with osteoanabolic agents improves outcomes Patients with a very high or imminent fracture risk should be considered for (first-line) therapy with ostoanabolic substances. Both patient selection and planning of therapy sequences are decisive factors for...…
