This content is machine translated Systemic lupus erythematosus Protection against relapses, even without remission The line between low disease activity and remission in systemic lupus erythematosus is often imprecise. The question remains to what extent this can play a role for outcomes such as…
View Post 2 min This content is machine translated Pancreatic Cancer Resection outcome and pCR rate improved Chemotherapy (CT) is the standard treatment for non-resectable, locally advanced pancreatic cancer. The CONKO-007 study investigated the role of sequential CT and chemoradiotherapy (CRT). The first results have now been…
View Post 5 min This content is machine translated Functional gastrointestinal disorders Large secondary analysis on peppermint oil A total of 157 publications were analyzed according to the PRISMA protocol, including randomized controlled trials, meta-analyses and case series. The authors conclude that peppermint oil is well suited as…
View Post 3 min This content is machine translated Rare diseases Brugada syndrome Brugada syndrome is an ion channel disorder in which there is an electrical disturbance of heart function without recognizable structural heart disease. This genetic heart rhythm disorder is associated with…
View Post 3 min This content is machine translated Case report: Disseminated strongyloidiasis Dwarf threadworm causes gastrointestinal pain Strongyloides stercoralis is a helminth that can parasitize humans and manifests itself through numerous symptoms. The course of the disease can be particularly severe in immunocompromised patients. A patient with…
View Post 4 min This content is machine translated Asthma-COPD-Overlap Coexisting disease entities instead of syndrome The concept of overlapping disease entities has changed and the term “asthma overlap syndrome” is no longer propagated. Patients who meet the diagnostic criteria for asthma and COPD should be…
View Post 4 min This content is machine translated Hand osteoarthritis: secondary analysis Oral NSAIDs and glucocorticoids as effective painkillers A research team from the University of Copenhagen conducted a secondary analysis based on data from 72 randomized studies with a total of over 7500 participants to investigate the effectiveness…
View Post 4 min This content is machine translated ESC update for SGLT-2-i Heart failure patients benefit regardless of LVEF The results of cardiovascular endpoint studies showing that dapagliflozin and empagliflozin significantly improve outcomes in HFpEF and HFmrEF have prompted the European Society of Cardiology (ESC) to adapt its recommendations.…
View Post 3 min This content is machine translated Tofacitinib for ulcerative colitis Study shows real-world evidence for efficacy and safety The prevalence of ulcerative colitis (CU) in Switzerland is 1/500. The JAK inhibitor tofacitinib has been an arrow in the treatment quiver since 2019. In the phase 3 OCTAVE study,…
View Post 4 min This content is machine translated Rare diseases Not all porphyria is the same This generic term covers molecular genetically extremely heterogeneous and predominantly hereditary metabolic diseases of heme biosynthesis, which are diagnosed and differentiated by specific biochemical patterns of porphyrins and porphyrin precursors…
View Post 3 min This content is machine translated Patient Blood Management Clarify and treat anemia and iron deficiency preoperatively The Patient Blood Management conceptpromoted by the World Health Organization offers opportunities in the healthcare sector to increase patient safety and at the same time reduce costs for the general…