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General Internal Medicine

1995 posts
  • This content is machine translated Iron deficiency

Update anemia workup: what, when, and why?

Iron deficiency anemia is common – especially in elderly patients with renal insufficiency or malnutrition. As a rule, a multifactorial process can be assumed. Therefore, a number of different causes…
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  • 3 min
  • This content is machine translated Relapsing-remitting multiple sclerosis (RRMS)

New S1P1 modulator expands the therapeutic spectrum

The selective sphingosine-1-phosphate receptor 1 (S1P1) modulator ponesimod has been approved in Switzerland since November 2021 for the treatment of relapsing-remitting multiple sclerosis (RRMS) with active disease. The approval is…
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  • 4 min
  • This content is machine translated Ischemic stroke

“Time is brain” – guideline recommendations for acute therapy.

Worldwide, strokes are among the leading causes of mortality and morbidity. In a new edition of the S2e guideline on acute therapy of ischemic insults, recommendations are given on the…
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  • 4 min
  • This content is machine translated Thrombocytopenia

New thrombopoietin receptor agonist available

Avatrombopag is an effective and safe second-line treatment for adult patients with chronic immune thrombocytopenia (ITP). In addition, this thrombopoietin receptor agonist can be used in adults with chronic liver…
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  • 4 min
  • This content is machine translated Irritable Bowel Syndrome

Network meta-analysis confirms therapeutic benefits of peppermint oil

Drug treatment of irritable bowel syndrome focuses on symptom relief. In this context, peppermint oil has proven to be an effective and well-tolerated therapeutic option. This has been demonstrated in…
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  • 3 min
  • This content is machine translated SARS-CoV-2

In vitro study of the effects of a bacterial lysate in human epithelial tissue.

Study results from a research team at the Department of Biomedicine at University Hospital Basel support the hypothesis that the bacterial lysate OM-85 may have utility in preventing SARS-CoV-2 infection…
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  • 5 min
  • This content is machine translated Modern lipid management

Treating dyslipidemia in diabetes in a target-oriented manner

Diabetes is associated with increased cardiovascular morbidity and mortality. Risk-stratified LDL cholesterol lowering is an important component of diabetes therapy and may improve clinical prognosis. In order to achieve the…
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  • 1 min
  • This content is machine translated High-risk cardiovascular patients.

Evolocumab stabilizes plaques in 90% of patients with acute coronary syndrome

After an acute coronary syndrome, patients are at high risk for further cardiovascular disease. Atherosclerotic plaques play a crucial role in this process, as up to 75% of acute coronary…
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  • 5 min
  • This content is machine translated Diabetes Technology

Hybrid closed-loop systems: more than glycemic control

The combination of continuous glucose monitoring (CGM) with a sensor-controlled insulin pump has already brought us a lot closer to the vision of an “artificial pancreas”. Compared to insulin pump…
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  • 5 min
  • This content is machine translated Outsourcing of complex patient cases

Centers for rare diseases

The National Coordination of Rare Diseases (kosek) has recognized three new Swiss centers for the evaluation of patients with unclear diagnoses and complex courses in 2021. Referrals are made by…
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  • 4 min
  • This content is machine translated Immuno-oncology

Immune checkpoint inhibitors in carcinoma patients – update for the primary care physician.

Therapy with anti-PD-1, anti-PDL-1 and anti-CTLA-4 antibodies can also achieve long-term remissions in patients with previously incurable tumor diseases. Whether a carcinoma patient will respond to treatment with checkpoint inhibitors…

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