This content is machine translated Eosinophils Severe asthmatics are more likely to suffer from systemic steroids If a diagnosis of severe asthma is confirmed, adjunctive therapy with monoclonal antibodies may be considered. Currently, anti-IgE or anti-IL5 antibodies are available for this purpose, depending on the phenotype.…
View Post 2 min This content is machine translated Iron deficiency Effective management of a cardio-renal patient. Heart failure often does not come alone. One third of the patients also suffer from renal insufficiency. A major challenge here is the iron deficiency that often occurs. Interdisciplinary management…
View Post 1 min This content is machine translated Hematologic neoplasms Differentiated diagnostics for effective results Differentiated diagnostic options are designed to enable therapy that is tailored to individual needs. However, in hematologic neoplasms, established treatment options are also effective.
View Post 10 min This content is machine translated Myeloproliferative neoplasms Polycythemia vera: pathogenesis, clinical, diagnostic and therapeutic implications. Hematopoietic stem cell myeloproliferative neoplasia is predominantly caused by somatic mutations of the JAK2 gene and resulting clonal autonomous hematopoiesis. The risk of myelofibrosis or leukemic transformation are prognostic.
View Post 3 min This content is machine translated Patient Blood Management Targeted treatment of preoperative anemia! Perioperative anemia, blood loss, and allogeneic blood transfusions are associated with increased postoperative morbidity and mortality and prolonged hospital stay. About 40% of patients undergoing major surgery are anemic. Target…
View Post 2 min This content is machine translated Iron supplementation In heart failure, think of iron deficiency (anemia)! Iron deficiency is a common comorbidity in patients with heart failure and has been associated with increased mortality and hospitalizations. The benefits and safety of iron supplementation were examined in…
View Post 2 min This content is machine translated Removal of pathogenic substances Lipoproteinapheresis – therapeutic option for familial hypercholesterolemia Patients with familial hypercholesterolemia in homozygous expression and patients with severe hypercholesterolemia require extracorporeal removal of pathogenic proteins, protein-bound pathogenic substances, or cells from the blood. Lipoprotein apheresis appears to…
View Post 8 min This content is machine translated Thrombophilia Antiphospholipid syndrome – an update. The systemic autoimmune disease APS (antiphospholipid syndrome) is mainly characterized by thrombotic manifestations. As acquired thrombophilia, variable drug thromboprophylaxis is indicated.
View Post 5 min This content is machine translated ASH in San Diego Pioneering study data on diffuse large B-cell lymphoma Among other things, new findings on the therapy of diffuse large B-cell lymphoma were presented. The phase III FLYER trial compared standard therapy (6xR-CHOP) with treatment reduced by two cycles…
View Post 2 min This content is machine translated Nanobody against autoimmune disease TTP New therapy for rare blood disease The autoimmune disease TTP is rare, life-threatening and difficult to treat. The results of a large phase III trial involving Inselspital Bern are now drawing attention to a new therapeutic…
View Post 8 min This content is machine translated Plasma cell myeloma Preferences in myeloma treatment in Switzerland 2018 With the approval of several new drugs, the treatment spectrum for second-line therapy of plasma cell myeloma has been expanded. In parallel, established treatment concepts, predominantly in first-line treatment, were…
