This content is machine translated SARS-CoV2 Omicron vs. influenza A/B Study compares risk of hospital mortality In a representative cohort study with data from more than 5000 hospitalized patients in Switzerland, the Corona variant Omicron was associated with a 1.5-fold increased risk of mortality compared with…
View Post 5 min This content is machine translated Systemic lupus erythematosus (SLE) Anifrolumab: 3-year data confirm long-term clinical benefit New data from a long-term extension study show that anifrolumab was effective, safe, and tolerable in systemic lupus erythematosus (SLE) even in long-term use over three years [1]. Two post-hoc…
View Post 6 min This content is machine translated Heart failure Dapagliflozin now approved in preserved ejection fraction [1,4]** After dapagliflozin had been approved for some time for heart failure with reduced ejection fraction, Swissmedic now granted an indication extension for heart failure with mildly reduced or preserved ejection…
View Post 3 min This content is machine translated Guselkumab in psoriatic arthritis Early response predicted Recent analyses of a heterogeneous group of patients with active psoriatic arthritis (PsA) show that early treatment response with respect to skin psoriasis and enthesitis is a predictor of sustained…
View Post 4 min This content is machine translated Pain therapy with non-opioid analgesics Benefit-risk assessment and patient education In Switzerland, paracetamol, non-steroidal anti-inflammatory drugs (NSAIDs) and metamizole are available as non-opioid analgesics. NSAIDs or metamizole should be considered if acetaminophen does not provide adequate pain relief. A differentiated…
View Post 4 min This content is machine translated Shingles Herpes zoster vaccine provides long-lasting protection for adults 50 and older Interim analysis of the follow-up phase of two phase III trials show that recombinant adjuvanted zoster vaccine protects against herpes zoster for at least 10 years overall after initial vaccination.…
View Post 5 min This content is machine translated Atopic dermatitis Tralokinumab – another biologic with an excellent benefit-risk profile Since the beginning of June this year, tralokinumab – a human monoclonal IgG4 antibody that specifically binds with high affinity to the cytokine IL-13 – has been approved for adults…
View Post 3 min This content is machine translated Antidepressant monotherapy Trazodone with innovative galenics achieves rapid and significant response The antidepressant monotherapy with trazodone achieves an effective response after only one week with a single daily dose starting at 150 mg. The multifunctional antidepressant mechanism of action of the serotonin…
View Post 1 min This content is machine translated Cardiovascular diseases New innovative treatment options Rising life expectancy worldwide is accompanied by an increasing medical need for effective treatments for cardiovascular diseases such as heart attack, stroke and heart failure (HF). Now, new innovative drugs…
View Post 2 min This content is machine translated Heart failure Novel approach leads to improvement in myocardial and vascular function In 2021, the European Society of Cardiology’s Heart Failure Guidelines Task Force published new guidelines mentioning heart failure exacerbations for the first time and emphasizing the urgency of accelerating the…
View Post 3 min This content is machine translated Pompe's disease Further development of enzyme replacement therapy provides new treatment option New data from the open-label, long-term extension of the randomized, double-blind, Phase 3 COMET study show that people with late-stage Pompe disease (LOPD) maintained improvements in respiratory function and mobility…
