This content is machine translated Chronic pain Identification of molecular mechanisms An epigenetic factor known as HDAC4 contributes to the development of chronic pain, as does an organic anion transporter (OAT1). The underlying molecular mechanism has been identified by a team…
View Post 6 min This content is machine translated Gliomas New indications for immuno-oncology? While immunotherapies are rapidly gaining ground in other entities, they are still in their infancy in CNS tumors. This is due in part to the often low immunogenicity. Nevertheless, antibody-based therapies,…
View Post 3 min This content is machine translated Ginkgo special extract Relief of tinnitus partially mediated by reduction of neuropsychiatric symptoms. A research team involving the Tinnitus Center at Charité-Universitätsmedizin Berlin (D) demonstrated in a mediation analysis that tinnitus patients benefit from treatment with a high-quality Ginkgo biloba extract, with efficacy…
View Post 3 min This content is machine translated Polyneuropathy Multidisciplinary therapy of a complex disease In polyneuropathies, all those parts of the nervous system that are outside the central nervous system are affected. In most cases, these impairments can be attributed to chronic alcohol abuse,…
View Post 3 min This content is machine translated Multiple sclerosis When movement is restricted: treatment options for spasticity Multiple sclerosis is the disease with a thousand faces. Not every patient is affected by every symptom. However, far too many sufferers often take the limitations for granted. For example,…
View Post 2 min This content is machine translated Neuroimmunology Mechanisms of neurodegeneration in the focus of multiple sclerosis. To date, not all details of the pathophysiology of multiple sclerosis have been fully elucidated. But one important finding has been made: the earlier you intervene in the disease, the…
View Post 2 min This content is machine translated Spinal muscular atrophy The disease in 2022 in the light of new therapeutic options In spinal muscular atrophy, insufficient SMN protein is provided due to a defect or loss of the SMN1 gene. As a result, motor neurons in the spinal cord and lower…
View Post 10 min This content is machine translated Dementia Clarification in practice Questions about brain performance due to subjective complaints or environment-reported cognition problems are increasingly common in primary care consultations. This is due to demographic developments. Dementias increase with age: 75-… CME-Test
View Post 4 min This content is machine translated Addiction and ADHD New digital paths in the therapy of comorbid diseases The digital transformation is in full swing. Intensive research is being conducted into new applications for virtual reality. Psychiatry in particular could benefit from the new technology. Addictive disorders and…
View Post 3 min This content is machine translated Diroximelfumarate (VumerityTM) in relapsing-remitting multiple sclerosis Current analysis confirms favorable benefit-risk profile For diroximel fumarate (VumerityTM), which has been approved for use by health insurers since November 1, 2021, an updated analysis of the phase III EVOLVE-MS-1 study was presented at the…
View Post 3 min This content is machine translated Migraine High underuse despite effective prevention options!? Migraine – a complex neurological disease that affects about 11% of the Western population. The impairment of the quality of life is as high as the suffering. Nevertheless, only a…
