This content is machine translated Guest article by the Foundation for People with Rare Diseases Ways of diagnostics – genetic testing for medical purposes The enormous progress made in recent years in the field of human genetics has already led to the identification of the cause of more than four thousand genetic (congenital) diseases.…
View Post 4 min This content is machine translated Malignant hematological diseases One tablet – no chemotherapy Will there soon be a once-daily tablet that will eliminate the need for chemotherapy for malignant hematologic diseases such as acute myeloid leukemia? This question is being investigated in an…
View Post 4 min This content is machine translated Mantle cell lymphoma First- and second-line lenalidomide Mantle cell lymphoma (MZL) is an aggressive non-Hodgkin’s lymphoma that accounts for approximately 3-6% of all NHL cases. It has a poor prognosis, especially after failure of first-line therapy. Lenalidomide…
View Post 8 min This content is machine translated Thymomas and thymic carcinomas Thymus tumors – diagnostics and therapy Thymic tumors are rare and belong to the so-called “orphan malignancies”. The annual incidence is approximately 0.15 per 100,000 persons. The latest classification distinguishes three major groups: Thymomas, thymic carcinomas…
View Post 2 min This content is machine translated Small papillary thyroid carcinomas Is active monitoring enough? There are some centers that advocate pursuing a strategy of active surveillance without surgery for small papillary thyroid carcinomas (PTC), which are increasingly encountered in clinical practice. A population-based cohort…
View Post 3 min This content is machine translated Rare Disease Day Step by Step December 2014 marked the 15th anniversary of European legislation on orphan drugs. Since that day, much has been achieved in Europe. In addition to EURORDIS – the European umbrella organization…
View Post 8 min This content is machine translated Therapies in geriatric oncology. Elderly patients with prostate or colorectal cancer As the population in Switzerland ages, even more people will develop cancer at an advanced age in the future. In these patients, treatment decisions are often complex because, due to…
View Post 7 min This content is machine translated Help via Internet Online interventions for cancer patients Internet-based interventions can help patients with certain diseases. The advantages of online interventions are their low-threshold nature, independence of time and place, and the absence of waiting times. In Switzerland,…
View Post 7 min This content is machine translated Immunological and molecular biological aspects MALT type gastric lymphoma MALT lymphomas most commonly affect the stomach. Causally, there is a strong association with Helicobacter pylori (Hp) gastritis (over 90% of patients). With adequate antibiosis, Hp can be eradicated, leading…
View Post 3 min This content is machine translated News from the ASH Congress on Nivolumab High response rates even in pretreated Hodgkin’s lymphomas Preclinical studies show that Sternberg-Reed cells, characteristic of classical Hodgkin lymphoma, use the PD-1 pathway to evade immunodetection. Therefore, immune checkpoint inhibitors such as nivolumab, which binds to the PD-1…
View Post 2 min This content is machine translated Immunosuppression in prostate cancer New therapeutic targets are being explored What is certain: The survival prognosis of metastatic castration-resistant prostate cancer (mCRPC) has improved – on average from just over one (before 2000) to almost three years [1]. Nevertheless, current…
