This content is machine translated Radical surgery as a treatment option Prophylactic mastectomy – for which patients is it an option? Prophylactic mastectomy reduces the risk of breast cancer by more than 95% in a healthy BRCA mutation carrier. However, intensified screening is a good alternative to surgery. For a diseased…
View Post 6 min This content is machine translated Genetic Diagnostics What is the importance of genes in the therapy of breast carcinoma? Oncotype DX®, MammaPrint® and EndoPredict® are validated gene assay tests with proven prognostic value. The use of the tests can currently be used in early breast carcinoma (Luminal A/B) in…
View Post 2 min This content is machine translated Men and cancer Infertility as a relevant risk factor Is male infertility a harbinger of cancer? The data situation is unclear. Several studies have shown that there is a higher risk of testicular cancer, but the relationship with other…
View Post 2 min This content is machine translated Non-steroidal anti-inflammatory drugs Do they protect against basal cell and squamous cell carcinomas? To date, there have been few epidemiologic studies examining the association between nonsteroidal anti-inflammatory drugs (NSAIDs) and fair skin cancer. However, since it is known that NSAIDs may well have…
View Post 3 min This content is machine translated HIV-associated lymphomas Stem cell transplantation is also a good therapy option for HIV patients At the ASH Congress in San Francisco, a study showed that HIV patients with relapsed or refractory lymphoma do not need to be treated differently than patients without HIV with…
View Post 4 min This content is machine translated Results from the ICE and SOFT studies Does capecitabine prove effective and who benefits from ovarian suppression? Two studies presented at the 2014 San Antonio Breast Cancer Symposium had been eagerly anticipated: ICE tested adjuvant monochemotherapy with capecitabine in an elderly patient population and SOFT tested ovarian…
View Post 4 min This content is machine translated Onco-training in St. Gallen Targeted systems therapy in metastatic NSCLC. In more than half of all patients with lung cancer, metastases are already present at the time of diagnosis. In recent years, new compounds have been developed that can be…
View Post 4 min This content is machine translated Prevention and treatment of ER-positive breast cancer IBIS-1 update shows promising results At the San Antonio Breast Cancer Symposium, people discussed prevention options for women at high risk for breast cancer. Tamoxifen continues to show a significant reduction in the incidence of…
View Post 3 min This content is machine translated Guest article by the Foundation for People with Rare Diseases Ways of diagnostics – genetic testing for medical purposes The enormous progress made in recent years in the field of human genetics has already led to the identification of the cause of more than four thousand genetic (congenital) diseases.…
View Post 4 min This content is machine translated Malignant hematological diseases One tablet – no chemotherapy Will there soon be a once-daily tablet that will eliminate the need for chemotherapy for malignant hematologic diseases such as acute myeloid leukemia? This question is being investigated in an…
View Post 4 min This content is machine translated Mantle cell lymphoma First- and second-line lenalidomide Mantle cell lymphoma (MZL) is an aggressive non-Hodgkin’s lymphoma that accounts for approximately 3-6% of all NHL cases. It has a poor prognosis, especially after failure of first-line therapy. Lenalidomide…
