This content is machine translated Metastatic renal cell carcinoma. What are the reasons for resistance to current drugs? Practical strategies for treatment management of metastatic renal cell carcinoma (mRCC) were presented at the ESMO Congress in Amsterdam. Updates on current clinical trials and the utility of new treatment…
View Post 5 min This content is machine translated New drugs Optimal use of kinase inhibitors How can kinase inhibitors be put to good use? What are the advantages or disadvantages of a combination? How can genomic sequencing contribute to an individualized therapeutic approach with such…
View Post 4 min This content is machine translated Highlights of the symposium at the Inselspital Bern How to respond to cervical cancer in pregnancy? The twelfth annual symposium of the Breast and Tumor Center at the Inselspital Bern, which was held at the end of December 2013, focused this time on cervical carcinoma. What…
View Post 5 min This content is machine translated Pancreatic adenocarcinoma The “borderline resectable” tumors as a specific challenge. At ASCO-GI in San Francisco, one of the topics was pancreatic adenocarcinoma. The so-called “borderline resectable” tumors were of particular interest. It is up for discussion whether primary surgery is…
View Post 6 min This content is machine translated Chronic lymphocytic leukemia and non-Hodgkin's lymphoma Updates on the active ingredients GA101 and rituximab Three studies on chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma were discussed at the ASH in New Orleans: One was an update on the stage 1 analysis of the CLL11…
View Post 4 min This content is machine translated Treatment of metastatic colorectal carcinoma. Patients with RAS wild type benefit in overall survival New data on first-line treatment of metastatic colorectal cancer were presented at the ASCO GI in San Francisco. The post-hoc analyses consistently confirm that RAS mutation status is an important…
View Post 4 min This content is machine translated Primary CNS lymphoma Advanced MRI diagnostics (spectroscopy, DWI, PWI) and MRI-guided biopsy. Introduction: Primary CNS lymphomas, predominantly of the B-cell type, are rare tumors with a peak incidence in middle to older age. Conventional MRI examination yields essentially nonspecific findings of a…
View Post 6 min This content is machine translated Tyrosine kinase inhibitors and the skin From common to rare side effects Epidermal-growth-factor receptors are found in the skin and sebaceous glands, tyrosine kinase (TK) in keratinizing skin, mucous membranes and hair, and are thus also targets of EGFR- and TK-inhibiting oncologics…
View Post 5 min This content is machine translated Barrett's esophagus and adenocarcinoma of the esophagus. Mucosal resection and radiofrequency ablation show very good long-term results Intestinal metaplasia, a so-called Barrette epithelium, can develop from normal esophageal squamous epithelium due to various factors. This may develop into low-grade or high-grade dysplasia, which in turn may be…
View Post 10 min This content is machine translated Treatment of epithelial ovarian cancer. Slow but steady progress Epithelial ovarian carcinoma is a heterogeneous group of carcinomas that have different etiology, genetics, and thus biological prognosis. In advanced stages (IIB-IV), the standard therapy remains maximal cytoreductive therapy, weighing…
View Post 7 min This content is machine translated HER2-positive breast carcinoma New substances enable targeted therapy The HER2 receptor belongs to the family of four transmembrane receptor tyrosine kinases (EGFR/HER1, HER2, HER3, and HER4) that influence cell growth, differentiation, and survival. Overexpression of HER2 occurs in…
