This content is machine translated Primary CNS lymphoma Advanced MRI diagnostics (spectroscopy, DWI, PWI) and MRI-guided biopsy. Introduction: Primary CNS lymphomas, predominantly of the B-cell type, are rare tumors with a peak incidence in middle to older age. Conventional MRI examination yields essentially nonspecific findings of a…
View Post 6 min This content is machine translated Tyrosine kinase inhibitors and the skin From common to rare side effects Epidermal-growth-factor receptors are found in the skin and sebaceous glands, tyrosine kinase (TK) in keratinizing skin, mucous membranes and hair, and are thus also targets of EGFR- and TK-inhibiting oncologics…
View Post 7 min This content is machine translated HER2-positive breast carcinoma New substances enable targeted therapy The HER2 receptor belongs to the family of four transmembrane receptor tyrosine kinases (EGFR/HER1, HER2, HER3, and HER4) that influence cell growth, differentiation, and survival. Overexpression of HER2 occurs in…
View Post 10 min This content is machine translated Treatment of epithelial ovarian cancer. Slow but steady progress Epithelial ovarian carcinoma is a heterogeneous group of carcinomas that have different etiology, genetics, and thus biological prognosis. In advanced stages (IIB-IV), the standard therapy remains maximal cytoreductive therapy, weighing…
View Post 3 min This content is machine translated Female tumors From the “old-fashioned” CMF to the modern T-DM1 Over the past two decades, the prognosis of breast carcinoma has improved significantly. As a rule, 75% of patients are cured today. The introduction of modern chemotherapeutic agents, particularly taxanes,…
View Post 2 min This content is machine translated Cancer organizations present results of comprehensive evaluation Excellent marks for the promotion of Swiss cancer research The Swiss Cancer Research Foundation and the Swiss Cancer League do an excellent job in promoting Swiss cancer research. They support research projects of excellent quality, resulting in many significant…
View Post 6 min This content is machine translated Actinic keratosis Short treatment duration significantly improves adherence Actinic keratosis (AK) is a premalignant lesion that is common in the fair-skinned population. In the U.S., cryotherapy is most commonly used to address the individual lesions. In addition, other…
View Post 4 min This content is machine translated ESMO Congress Aspirin – a miracle drug in the fight against cancer? Evidence is accumulating that Aspirin® may be effective in cancer prevention, as well as in inhibiting metastases. One of the most renowned researchers and best-known representatives of this new optimism…
View Post 4 min This content is machine translated Multiple Myeloma and MDS Something has happened in therapy The diagnosis and treatment of multiple myeloma (MM) and myelodysplastic syndromes (MDS) have undergone great development in recent years. Modern diagnostic procedures became qualitatively better and more widely available, new…
View Post 4 min This content is machine translated HER2-positive breast cancer and lymphoma New applications and antibodies The antibody-drug conjugate trastuzumab emtansine, T-DM1 (Kadcyla®), is composed of the antibody trastuzumab and the chemotherapeutic agent DM1 and is currently being investigated for the treatment of HER2-positive cancers. It…
View Post 3 min This content is machine translated Actinic keratosis Physicians should reconsider their therapy habits At this year’s Melanoma Congress in Hamburg, the question was raised whether the most commonly used treatment options for actinic keratosis (AK) are the most effective and cost-effective. Furthermore, the…