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Pharmacology and toxicology

255 posts
  • This content is machine translated Pain Management

Tumor pain – a therapeutic challenge that affects everyone

The survival times of malignant patients have increased significantly in recent years due to the improvement of therapy options. However, about one in two patients develops tumor pain in the…
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  • 5 min
  • This content is machine translated Medicinal products containing cannabis

Miracle cure or marketing hype?

Globally, there is a trend toward increased use of preparations containing cannabis. Indications include pain problems or spasticity in the context of neurological diseases. Adverse effects are strongly dose-dependent.
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  • 10 min
  • This content is machine translated Phytotherapy for depression

Low risk of interaction with low-hyperforin St. John’s wort

St. John’s wort extracts are proven for the treatment of depressive disorders. However, some preparations, by inducing CYP3A4 and P-glycoprotein (ABCB1), lower the plasma levels of other drugs and impair…
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  • 4 min
  • This content is machine translated Drug reactions

From toots and bubbles anaphylaxis

The lethality to drug reactions is 10%. Drug allergies and anaphylaxis thus form a complex of topics that must be dealt with urgently in clinics and practices, as the consequences…
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  • 3 min
  • This content is machine translated Therapeutic Drug Monitoring

For which psychotropic drugs are blood level controls useful?

Determining blood levels of medications is not only mandatory for some psychotropic drugs, but overall can be very helpful in providing effective therapy. For which preparations may therapeutic drug monitoring…
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  • 2 min
  • This content is machine translated Rhinovirus infection

Fight off acute respiratory infections naturally through immune stimulation

Colds are caused by rhinoviruses in 70% of cases. Typically, the disease lasts 10 to 14 days and numerous treatment options are not very effective. Patients with asthma or COPD…
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  • 9 min
  • This content is machine translated New in the treatment of schizophrenia

Similarities and differences among partial dopamine agonists.

Antipsychotics are the mainstay of acute and long-term treatment for schizophrenic disorders. The earlier antipsychotic treatment begins, the greater the chance of controlling or stopping the progression of psychosis.
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  • 2 min
  • This content is machine translated Application for approval

Alzheimer’s drug to be submitted for approval

After consultation with the U.S. Food and Drug Administration (FDA), the manufacturer Biogen plans to submit aducanumab for approval. The Phase 3 EMERGE study met its primary endpoint and demonstrated…
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  • 7 min
  • This content is machine translated Special case migraine

Do not take headaches in children lightly

Headaches in children are often underestimated, but occur frequently with a prevalence of 79%. Due to genetic predisposition and functional impairment already from (pre-)school age, migraine is the most important.…
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  • 17 min
  • This content is machine translated Migraine prophylaxis with medication

Challenge and opportunity

In the case of frequent headaches, prophylactic medication may be useful. What medications are available and what is the evidence for their efficacy?
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  • 9 min
  • This content is machine translated Warning signs for drug allergies

Hypersensitivity to drugs – main forms and warning signs

Severe drug allergies can be potentially life-threatening, so early detection and treatment is very important. In many cases, these are rather harmless exanthems. However, in 2-5% of cases, these are…

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