This content is machine translated Application for approval Alzheimer’s drug to be submitted for approval After consultation with the U.S. Food and Drug Administration (FDA), the manufacturer Biogen plans to submit aducanumab for approval. The Phase 3 EMERGE study met its primary endpoint and demonstrated…
View Post 7 min This content is machine translated Special case migraine Do not take headaches in children lightly Headaches in children are often underestimated, but occur frequently with a prevalence of 79%. Due to genetic predisposition and functional impairment already from (pre-)school age, migraine is the most important.…
View Post 17 min This content is machine translated Migraine prophylaxis with medication Challenge and opportunity In the case of frequent headaches, prophylactic medication may be useful. What medications are available and what is the evidence for their efficacy?
View Post 9 min This content is machine translated Warning signs for drug allergies Hypersensitivity to drugs – main forms and warning signs Severe drug allergies can be potentially life-threatening, so early detection and treatment is very important. In many cases, these are rather harmless exanthems. However, in 2-5% of cases, these are…
View Post 12 min This content is machine translated Drug Safety Drug interactions in oncology Drugs with a narrow therapeutic range, such as those frequently used in oncology, require a basic knowledge of possible interactions with other preparations. Pharmacodynamics and pharmacokinetics should not be foreign…
View Post 5 min This content is machine translated Rational use of antidepressants First wait and see, then intervene with medication Antidepressants are prescribed too often – contrary to the study evidence, which attests only low efficacy of the commonly used agents in mild depressive episodes, and contrary to the guideline…
View Post 2 min This content is machine translated "Crystalline Sponge" technology Merck & Rigaku: Pioneering innovation project launched The goal of the strategic partnership is to make the complex “Crystalline Sponge” technology available to laboratories in the chemical and life science industries for the analysis of molecular structures…
View Post 3 min This content is machine translated Dangers of multimedication Pay attention to interactions According to the WHO definition, more than 5 drugs per day is considered polypharmacotherapy and is especially common in elderly patients. In the over-70 age group, up to half of…
View Post 5 min This content is machine translated Interdisciplinary pain management Keeping an eye on the dependence potential of analgesics Findings from interdisciplinary pain research are also relevant to everyday dermatological practice. As with other indications, effects and side effects should be carefully weighed in this context (e.g., risk of…
View Post 8 min This content is machine translated Pharmacologic management of unipolar depression. Acting with a biopsychosocial perspective Pharmacotherapy for depression is part of an overall treatment process based on a biopsychosocial model. In general, the more severe the depression, the higher the evidence for antidepressant treatment.
View Post 6 min This content is machine translated Therapeutic drug monitoring in neuropsychopharmacology. New consensus guidelines from the AGNP TDM working group. The determination of psychotropic drugs in the blood (therapeutic drug monitoring, TDM) contributes to an optimal and personalized therapy of the psychiatric patient. This article presents a brief introduction to…
