This content is machine translated Chronic renal failure Dapagliflozin meets primary endpoints ahead of schedule The Phase III DAPA-CKD study will be terminated earlier than planned due to proven efficacy in patients with chronic renal failure. Dapagliflozin is the first SGLT2 inhibitor to show meaningful…
View Post 3 min This content is machine translated White skin cancer Imiquimod durably effective in superficial basal cell carcinoma Findings from long-term studies demonstrate the sustained therapeutic success of the toll-like receptor agonist imiquimod in the indication area of small superficial basal cell carcinomas. Early detection and treatment is…
View Post 4 min This content is machine translated COPD treatment Fewer exacerbations with mucolytics Mucolytics are included in several guidelines as a treatment option for patients with frequent exacerbations. According to GOLD, they can reduce exacerbations and marginally improve health status. However, evidence is…
View Post 6 min This content is machine translated Type 2 diabetes: SGED Recommendations 2020 Update Cardiovascular risk stratification and personalized therapy. When prescribing antidiabetic therapy, other criteria are relevant today in addition to blood glucose control. The cardiac benefit of SGLT2 inhibitors and GLP1 analogues has been incorporated into international guidelines…
View Post 4 min This content is machine translated Cystic fibrosis Even one mutated gene increases the risk In autosomal recessive diseases such as cystic fibrosis (CF), one is dealing with the inheritance of two mutated genes. Previously, CFTR* expression levels of 50% were thought to be sufficient…
View Post 6 min This content is machine translated Inflammatory dermatoses Not only the right wavelength is decisive Laser medicine applications as second-line or adjuvant therapy can be a valuable addition to the treatment spectrum for inflammatory dermatoses. For best possible results, treatment decisions must be weighed on…
View Post 3 min This content is machine translated Rheumatic diseases How do antirheumatic drugs correlate with COVID-19 courses? Whether the use of immunosuppressants increases the risk of a severe course in SARS-CoV-2 infection is as yet unclear. A study published in advance of the European Congress of Rheumatology…
View Post 3 min This content is machine translated Dizziness With ginkgo extract against swaying soils Dizziness is one of the unpleasant side effects of aging. Usually, disorders in the vestibular system or balance perception are responsible. However, it may also be a result of declining…
View Post 5 min This content is machine translated Chronic sialorrhea Approval: Ultrasound-guided injection of incobotulinumtoxinA In numerous neurological conditions such as Parkinson’s syndromes, stroke or traumatic brain injury, impaired sialorrhea may occur. IncobotulinumtoxinA is the first drug to be approved in Switzerland for the treatment…
View Post 3 min This content is machine translated Acne “Comedo-Switch” concept as basis of topical therapy The analysis of comedogenesis at the cellular level is of practical relevance, as new starting points for therapies can be elicited on this basis. In addition, empirical validation of comedolytic…
View Post 3 min This content is machine translated Cancer treatment Light therapy for immune cells helps with side effects Autoimmune reactions are a common side effect of checkpoint inhibitor therapies used to treat melanocytic tumors. As a study published in the New England Journal of Medicine shows, extracorporeal photopheresis…