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Posts by tag

COMT inhibitors

5 posts
  • This content is machine translated Parkinson's

Pathophysiology, classification and effective treatment strategies

Parkinson’s disease is clinically defined by the main motor symptoms resulting from nigrostriatal degeneration. However, it is now assumed that the disease usually consists of several pathologies. What new findings…
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  • 3 min
  • This content is machine translated Parkinson's

The treatment of L-dopa associated effect fluctuations.

Parkinson’s patients suffer the most from effect fluctuations. However, it is not possible to predict when this phase begins due to the individual course of the disease. Several starting points…
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  • 15 min
  • This content is machine translated Parkinson's disease

Place of COMT inhibitors in Parkinson’s disease therapy.

Over time, fluctuations in efficacy may occur in Parkinson’s therapy with L-dopa. Then, the treatment of L-dopa induced dyskinesias and motor fluctuations represents the most important task in clinical practice.…
CME-Test
View Post
  • 3 min
  • This content is machine translated Parkinson's

From clinical syndrome to molecular diagnostics and modern therapy

A large proportion of Parkinson’s patients suffer from the sporadic form of the disease, in which no gene mutations can be detected. However, in order to develop drugs using cell…
View Post
  • 2 min
  • This content is machine translated Parkinson's disease

BRIVARACT II study on opicapone

Purpose: A large proportion of patients with Mb. Parkinson’s disease experiences fluctuations in the effect of levodopa therapy during the course of the disease.
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