This content is machine translated Friedreich's ataxia Interim analyses of the PROFA study show “Unmet needs” The PROFA study focuses, among other things, on patient-reported psychosocial effects of Friedreich’s ataxia (FRDA) at different stages of the disease. The study comprises a cohort of FRDA patients in...…
View Post 5 min This content is machine translated Ataxias Friedreich’s ataxia: when the energy metabolism attacks the nervous system Energy deficiency instead of pure oxidative stress: New data show that in Friedreich’s ataxia, disturbances in fatty acid and ketone body metabolism in particular contribute to selective neurodegeneration. The article...…
View Post 7 min This content is machine translated From biomarkers to gene therapies Getting to know ataxias New developments in imaging, digital biomarkers and gene therapy are significantly changing the diagnosis and treatment of ataxia. Experts emphasize the clinically central distinction between sensitive and cerebellar ataxia, the...…
View Post 4 min This content is machine translated Friedreich's ataxia Loss of orientation in the cerebellum Spinocerebellar ataxias represent a large group of rare, progressive neurodegenerative diseases that affect the cerebellum and its connections and predominantly manifest themselves in a cerebellar syndrome. In addition to progressive...…
View Post 3 min This content is machine translated Friedreich's ataxia Treatment options have improved Friedreich’s ataxia is a hereditary neurodegenerative disease that is classically characterized by uncoordinated movements, postural and gait disorders, as well as balance and visual disorders. Subgroups of those affected also...…
View Post 5 min This content is machine translated Findings from the TRACK-FA study Neuroimaging biomarkers in Friedreich’s ataxia Friedreich’s ataxia (FA) is a rare, autosomal recessive neurodegenerative disease whose natural history and clinical characterization have made significant progress in recent decades. Nevertheless, there is still a lack of...…
