Loss of orientation in the cerebellum

Spinocerebellar ataxias represent a large group of rare, progressive neurodegenerative diseases that affect the cerebellum and its connections and predominantly manifest themselves in a cerebellar syndrome. In addition to progressive motor disability, which manifests itself in unsteady gait, limb incoordination or dysarthria, the disease is often accompanied by cerebellar cognitive-affective syndrome. This encompasses a spectrum of cognitive and neuropsychiatric deficits, with impairment of executive, linguistic and visuospatial functions in the foreground.