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Posts by tag

JAK Inhibitor

6 posts
  • This content is machine translated Therapy with Small Molecules

JAK inhibitors in inflammatory dermatoses on the rise

In inflammatory processes of dermatological diseases, pro-inflammatory cytokines play a central role. Therefore they are in focus therapeutic approaches when it comes to breaking critical signaling pathways. In addition to monoclonal…
View Post
  • 4 min
  • This content is machine translated Atopic dermatitis

Long-term efficacy of baricitinib proven

In adult patients with moderate to severe atopic dermatitis, long-term therapy with the JAK inhibitor baricitinib maintained improvements achieved after 16 weeks for 68 weeks, new data show. A pooled…
View Post
  • 5 min
  • This content is machine translated Moderate to severe atopic dermatitis

Biologic therapy in the changing times: “Best practice” approaches in focus

In addition to the new systemic drugs recently launched, several active substances are currently in development. These include some biologics in advanced stages of clinical testing. Overall, the future prospects…
View Post
  • 4 min
  • This content is machine translated Atopic dermatitis

JAK inhibition as a mode of action – an update.

Janus kinase (JAK) inhibitors are a promising new treatment option for adult patients with atopic eczema, given their rapid relief of pruritus and inflammatory lesions. In addition to baricitinib, which…
View Post
  • 3 min
  • This content is machine translated Baricitinib

First oral JAK inhibitor approved for the treatment of atopic dermatitis

The use of small molecule drugs for the treatment of atopic dermatitis has been investigated for some time. With the approval of the Janus kinase (JAK) inhibitor baricitinib, a new…
View Post
  • 5 min
  • This content is machine translated Myelofibrosis

Treatment in transition

With the introduction of the Janus kinase (JAK) inhibitor ruxolitinib, therapy for myelofibrosis has changed dramatically in recent years. Nevertheless, further innovation is needed, especially in the second line. Promising…
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