This content is machine translated Non-small cell lung cancer and other solid tumors In the pipeline: KRAS G12C inhibitor Sotorasib The KRAS gene is one of the most frequently mutated oncogenes in human cancers and thus represents a promising target in the therapy of diverse solid tumors. Sotorasib is currently…
View Post 4 min This content is machine translated Onco-Training St. Gallen News on metastatic colorectal cancer Metastatic colorectal cancer was the focus of an afternoon symposium in St. Gallen. Significant progress has been made in the field of colorectal cancer therapy in recent years, but this…
View Post 4 min This content is machine translated Metastatic colorectal cancer Which first-line therapy for patients with wild-type RAS? At this year’s ESMO Congress in Madrid, treatment options for metastatic colorectal cancer were also discussed. Is there an optimal strategy for patients with a wild-type RAS mutation, and would…
View Post 4 min This content is machine translated Metastatic colorectal cancer Comparison between bevacizumab and cetuximab in KRAS exon2 wild type. According to preliminary results of a large phase III trial presented at this year’s ASCO congress, bevacizumab and cetuximab (combined with FOLFOX or FOLFIRI) show similar efficacy in terms of…
View Post 7 min This content is machine translated Metastatic non-small cell lung cancer Drug therapy 2014 Determination of EGFR mutational status and EML-ALK translocations in patients with metastatic adenocarcinoma has therapeutic implications and should be requested at diagnosis. Maintenance treatment with pemetrexed in patients with non-squamous…
View Post 2 min This content is machine translated Lung Cancer An evaluation of current diagnostic and therapeutic strategies. This issue of InFo ONKOLOGIE & HÄMATOLOGIE is about lung cancer. In view of the high prevalence – in men it is still the most common malignancy of all –…
View Post 5 min This content is machine translated New drugs Optimal use of kinase inhibitors How can kinase inhibitors be put to good use? What are the advantages or disadvantages of a combination? How can genomic sequencing contribute to an individualized therapeutic approach with such…
View Post 4 min This content is machine translated Treatment of metastatic colorectal carcinoma. Patients with RAS wild type benefit in overall survival New data on first-line treatment of metastatic colorectal cancer were presented at the ASCO GI in San Francisco. The post-hoc analyses consistently confirm that RAS mutation status is an important…
