This content is machine translated Paroxysmal nocturnal hemoglobinuria (PNH) From iron deficiency to diagnosis Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired disease characterized by intravascular hemolysis and hemoglobinuria. Due to a prolonged loss of hemoglobin through the urine, PNH can lead to iron…
View Post 2 min This content is machine translated Paroxysmal Nocturnal Hemoglobinuria Relief for patients due to longer infusion intervals Chronic destruction of red blood cells is characteristic of paroxysmal nocturnal hemoglobinuria. Mutations in the PIG-A gene lead to a GPI-AP deficit that results in uncontrolled complement activation. C5 complement…
