This content is machine translated GPP: from molecular principles to targeted therapy Therapeutic rationale for targeted IL-36 receptor inhibition The progress in the diagnosis and treatment of generalized pustular psoriasis (GPP) is remarkable. GPP has developed into a clearly defined, independent, IL-36-mediated autoinflammatory disease. Today, the high chronic disease...…
View Post 4 min This content is machine translated Pustular psoriasis What is known about inflammatory mechanisms in PPP and GPP? Pustular psoriasis is characterized by the sudden appearance of small, pus-filled blisters (“pustules”). The clinical, pathological and genetic features of GPP and PPP differ from plaque psoriasis. While in GPP...…
