This content is machine translated "Small Molecules" at AD Current analyses of the pioneer among the JAK-i The first representative of the Janus kinase (JAK) inhibitor class to be approved for atopic dermatitis was baricitinib. In an extensive study program, this selective and reversible inhibitor of JAK-1…
View Post 7 min This content is machine translated Dermatomyositis Diagnostics and treatment – a current overview Pathognomonic skin signs of dermatomyositis include heliotrope erythema, Gottron papules, and Gottron signs. The determination of myositis-specific autoantibodies has an increasingly important role in the diagnosis. Regarding treatment options, intravenous…
View Post 16 min This content is machine translated Moderate to severe atopic dermatitis Changing therapeutic landscape – broad arsenal of treatment options New therapies in the form of specific antibodies and “small molecules” have ushered in a new era. Biologics intervene in the inflammatory process of atopic dermatitis by targeting individual cytokines.… CME-Test
View Post 4 min This content is machine translated Therapy with Small Molecules JAK inhibitors in inflammatory dermatoses on the rise In inflammatory processes of dermatological diseases, pro-inflammatory cytokines play a central role. Therefore they are in focus therapeutic approaches when it comes to breaking critical signaling pathways. In addition to monoclonal…
View Post 5 min This content is machine translated Rheumatoid arthritis Halting joint destruction through early use of DMARDs Early adequate therapy of rheumatoid arthritis (RA) is of central importance for the entire further course of the disease, current guidelines conclude. After diagnosis, the indication for disease-modifying therapy should…
View Post 3 min This content is machine translated "Small Molecules" for the Treatment of Psoriasis Oral and topical drug candidates score well in studies As in today’s era of personalized medicine a treatment tailored to the individual needs of psoriasis patients is important, there are several arguments for a use of small molecule substances.…
View Post 6 min This content is machine translated Psoriasis as an inflammatory systemic disease Changing disease concept – implications for biologic therapy. Psoriasis is nowadays no longer understood as an exclusive skin disease, but rather as a systemic disease. Biologics specifically intervene in the disease process and have revolutionized treatment options. When…
View Post 10 min This content is machine translated Chronic inflammatory bowel disease (CED) Modern “State-of-the-Art” Pharmacotherapy – an Update Modern approaches to the treatment of inflammatory bowel disease (IBD) are based on the motto “treat-to-target”, whereby in addition to symptom relief and induction of disease remission, the aim nowadays… CME-Test
View Post 5 min This content is machine translated Moderate and severe plaque psoriasis From Immunopathogenesis to Highly Effective Therapies – Enduring Lesion Freedom as the Goal Translational approaches have revolutionized the treatment options for psoriasis. New findings in the field of epidermal immunopathology form the basis for the optimization of highly effective substances. The new generation…
