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Allergology and clinical immunology

458 posts
  • This content is machine translated Atopic dermatitis

JAK inhibition as a mode of action – an update.

Janus kinase (JAK) inhibitors are a promising new treatment option for adult patients with atopic eczema, given their rapid relief of pruritus and inflammatory lesions. In addition to baricitinib, which…
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  • 4 min
  • This content is machine translated Allergic rhinitis

Nose runs – research too

Allergic rhinitis (AR) is one of the most common diseases in the world with an incidence of 10% to 40% in the population. Upper respiratory tract disease is manifested by…
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  • 12 min
  • This content is machine translated Atopic dermatitis

Digital support options for treatment

The terms atopic dermatitis, atopic eczema and atopic dermatitis stand for a global skin disease, with children and adolescents being the most frequently affected. In 2020, a systematic review included…
CME-Test
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  • 3 min
  • This content is machine translated Phase IIa study

Tocilizumab for the treatment of Schnitzler syndrome

Schnitzler syndrome is a rare autoinflammatory disorder. Core symptoms include chronic, recurrent hives. In particular, for patients who do not respond to anti-IL1 therapy, there is a need for new…
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  • 5 min
  • This content is machine translated Dust mite allergy

Tiny components with a big impact

Dust mite allergy is characterized by year-round symptoms of the nose, lungs and/or eyes. Inadequate diagnosis and treatment may favor the development of allergic asthma (“floor change”). If symptomatic therapy…
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  • 4 min
  • This content is machine translated Sublingual immunotherapy

New pill against the mite

The past year has not brought much news in terms of large studies on sublingual immunotherapy (SLIT) that are suitable for approval. There were new findings, particularly on the effect…
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  • 15 min
  • This content is machine translated Self-management of teens with allergies or asthma

Somehow it doesn’t work: adherence and compliance in adolescents

Adolescents are difficult, don’t want to go to therapy, are unmotivated, are non-compliant: this is our common image of chronically ill adolescents. Is that really so? Or maybe it’s the…
CME-Test
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  • 3 min
  • This content is machine translated Allergic rhinitis: sublingual specific immunotherapy

Allergen extracts melt under the tongue

Allergen-specific immunotherapy is currently the only causal therapy for the treatment of immediate-type allergies such as allergic rhinitis. In contrast to symptomatic therapies, the goal is to achieve sustained immunological…
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  • 6 min
  • This content is machine translated Dupilumab for the treatment of atopic dermatitis

Reduction of Th2-mediated inflammation – therapeutic success also in adolescents

Th2-mediated inflammatory processes play a central pathogenetic role in atopic dermatitis. This is the therapeutic target of the IL4/IL13 inhibitor dupilumab, which was recently approved in Switzerland also for adolescents…
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  • 3 min
  • This content is machine translated Baricitinib

First oral JAK inhibitor approved for the treatment of atopic dermatitis

The use of small molecule drugs for the treatment of atopic dermatitis has been investigated for some time. With the approval of the Janus kinase (JAK) inhibitor baricitinib, a new…
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  • 6 min
  • This content is machine translated Hand eczema

Prevent chronification through early use of topical topical topicals

Hand eczema is associated with psychosocial and socioeconomic follow-up costs. The corona pandemic has significantly increased the prevalence of hand eczema. Affected persons and risk groups should be informed in…

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