This content is machine translated Prurigo nodularis Inflammation-promoting pruritogenic cytokines as a therapeutic target There are various triggers for the initial itching in prurigo nodularis (PN). If those affected give in to the scratching impulse, the pruritus intensifies, as this stimulates nerve and inflammatory…
View Post 7 min This content is machine translated Atopic dermatitis: guideline update Current recommendations on biologics and JAK inhibitors With the increasing number of system therapeutics, practical advice on choosing the most suitable treatment option is becoming more important. The new edition of the S3 guideline on atopic dermatitis…
View Post 10 min This content is machine translated Hand eczema: Guideline 2023 Therapy depends on the severity The new edition of the guideline “Diagnosis, prevention and treatment of hand eczema”, which was published this year under the auspices of the German Dermatological Society, focuses in particular on…
View Post 5 min This content is machine translated Atopic dermatitis Focus on mediators of type 2 inflammation The pathomechanisms of atopic dermatitis (AD) are becoming increasingly better understood. A genetically determined immunological imbalance is characterized by an increased Th2 response and is associated with the production of…
View Post 3 min This content is machine translated Journal Club Atopic dermatitis and the skin microbiome: new study findings Exploring the links between the cutaneous microbiome and the severity of atopic dermatitis (AD) and patient-related co-factors is an important aspect in the development of new personalized AD therapies, especially…
View Post 6 min This content is machine translated Chronic urticaria “Treat-to-target” approach is underpinned by new findings The treatment arsenal for chronic urticaria includes several 2nd generation antihistamines – still the treatment of first choice – the monoclonal antibody Omalizumab and the immunosuppressant Ciclosporin A as an…
View Post 5 min This content is machine translated Case reports: Pityriasis rubra pilaris (PRP) Supposedly therapy-resistant PRP responded to biologic treatment The treatment of pityriasis rubra pilaris can be a challenge. The therapeutic arsenal includes topical corticosteroids, phototherapy or classic systemic therapies such as retinoids or immunosuppressants. Recent case reports and…
View Post 5 min This content is machine translated Prurigo nodularis New therapeutic approaches are promising Recent research findings indicate that Th2-associated immune cells and cytokines play an important role in the pathogenesis of prurigo nodularis (PN). This is the therapeutic target of the two biologics,…
View Post 7 min This content is machine translated Update allergology Management of allergies in the era of precision medicine In the context of molecular allergy diagnostics, IgE antibodies against individual allergen components are determined. This offers added value, especially for patients with multiple sensitizations. Allergen-specific immunotherapy is available in…
View Post 16 min This content is machine translated Invasive pulmonary aspergillosis Correctly diagnose and treat IPA Aspergillus species can cause a variety of diseases. Among these, invasive pulmonary aspergillosis (IPA) is the most common opportunistic infection caused by moulds in immunocompromised patients and is characterized by… CME-Test
View Post 3 min This content is machine translated Study Report Dupilumab in 6- to 11-year-old AD patients: Effects on skin barrier function Atopic dermatitis (AD) is one of the most common diseases in childhood and adolescence. An observational study evaluated the effects of dupilumab in a subpopulation of 6–11-year-old patients with moderate-to-severe…
