This content is machine translated Chronic Hepatitis B: Is a Cure in Sight? Phase III Trial of Temporary Treatment with Bepirovirsen Was Successful Hepatitis B is the most common form of viral hepatitis worldwide—dreaded complications include liver cirrhosis and hepatocellular carcinoma (HCC). Treatment with Bepirovirsen, an antisense oligonucleotide that targets mRNAs of the...…
View Post 5 min This content is machine translated Clinically Suspected Arthralgias “Watchful waiting” or intervention? The pathogenesis of rheumatoid arthritis (RA) begins years before clinical manifestation, but not all patients with joint pain develop RA. Since the primary care physician or internist’s office is usually...…
View Post 6 min This content is machine translated Upper GI Tract Bleeding: Hematemesis, Hematochezia, or Melena? From Risk Stratification to Post-Endoscopic Management Managing patients with acute upper gastrointestinal bleeding can be a balancing act. Clinical scores are helpful for time-sensitive risk assessment in the emergency department: Is the patient stable? Is urgent...…
View Post 5 min This content is machine translated From Hypertension to Heart Failure? When and how to intervene High blood pressure and hypertensive heart disease are the most significant risk factors for heart failure. The symptoms are very nonspecific, especially in the early stages of heart failure. Measuring...…
View Post 4 min This content is machine translated CKD and High Blood Pressure Keeping an Eye on Bidirectional Interactions Both hypertension and chronic kidney disease (CKD) are asymptomatic for long periods of time but pose serious health risks, underscoring the importance of timely screening in primary care. In this...…
View Post 3 min This content is machine translated Atherosclerotic Coronary Plaques in High-Risk Patients Who benefits from preventive PCI? For patients with ASCVD, modern imaging techniques such as CCTA and cardiac MRI often provide a solid basis for subsequent treatment decisions. The invasive cardiac catheterization procedure is currently used...…
This content is machine translated Ischemic stroke: Are smaller or larger brain arteries affected? Recent study findings on intravenous lysis therapy with fibrinolytic agents Intravenous thrombolysis, with or without mechanical thrombectomy, is a key pillar in the treatment of ischemic stroke. There are now two approved treatment options available—alteplase and tenecteplase—and Phase II data...…
View Post 8 min This content is machine translated Modern asthma therapies New data on biologics and triple therapy The treatment of severe asthma is increasingly moving towards individualized and low-steroid treatment concepts. Current developments in biologics and modern inhaled therapy strategies were highlighted at the DGP Congress 2026....…
View Post 5 min This content is machine translated Long COVID/Fatigue Clinic An Innovative Approach: Neuroplasticity and Predictive Processing At the University Hospital of Basel (USB), a promising neuroplastic therapeutic approach is being tested as part of the fatigue clinic. Based on the fundamental assumption that while fatigue and...…
View Post 7 min This content is machine translated Non-anginal chest pain: Could it be a heart attack? From Triage to Secondary Prevention—A Recent Update In cases of chest pain caused by coronary insufficiency, acute coronary syndrome (ACS) should be considered. There is an increased risk in men aged ≥55 and women aged ≥65, as...…
View Post 6 min This content is machine translated Myasthenia gravis: immunomodulatory therapies for long-term treatment Expanded Possibilities Thanks to Innovative Classes of Active Ingredients Myasthenic syndromes result from a disturbance in neuromuscular transmission. Although there is still no curative treatment for myasthenia gravis, the drug treatment options available today offer tailored therapeutic approaches aimed...…
