This content is machine translated Prurigo nodularis and AD Effective itch relief through inhibition of the IL-31 signaling pathway The vicious circle of itching and scratching is a central element in both prurigo nodularis (PN) and atopic dermatitis (AD). Interleukin (IL)-31, often referred to as the “itch cytokine”, has...…
View Post 2 min This content is machine translated IBD and SARS-CoV-2 Vulnerable at the mercy of others While COVID-19 mRNA vaccines induce a robust systemic immune response in patients with inflammatory bowel disease (IBD), little is known about their efficacy in the mucosal immune system. Researchers have...…
View Post 8 min This content is machine translated GPP: from molecular principles to targeted therapy Therapeutic rationale for targeted IL-36 receptor inhibition The progress in the diagnosis and treatment of generalized pustular psoriasis (GPP) is remarkable. GPP has developed into a clearly defined, independent, IL-36-mediated autoinflammatory disease. Today, the high chronic disease...…
View Post 6 min This content is machine translated Chronic insomnia in adults: Guideline recommendations CBT-i as first choice – pharmacotherapy as secondary intervention Sleep disorders are often associated with pronounced daytime sleepiness, difficulty concentrating and increased feelings of stress. Diagnosis is generally based on the clinical history; if necessary, an actigraphy or polysomnigraphy...…
View Post 5 min This content is machine translated Nutrition for type 2 diabetes Not such a great tuber The link between potato consumption and the risk of type 2 diabetes has long been debated. Although potatoes are a staple food worldwide, rich in starch and with a high...…
View Post 3 min This content is machine translated Type 2 diabetes Smoking causes more than double the risk The characteristics of type 2 diabetes vary from patient to patient and the disease is thought to consist of four subtypes. However, a new study shows that smoking significantly increases...…
View Post 6 min This content is machine translated Colorectal cancer Is exercise better than medication? The presentation by a renowned Canadian oncologist on promising treatment options for colorectal cancer through exercise therapy caused quite a stir at this year’s ASCO. The results of a randomized...…
View Post 7 min This content is machine translated Atrial fibrillation: interdisciplinary effort is crucial Managing risk factors and comorbidities in addition to rhythm control The previously used “ABC” scheme was replaced by the more comprehensive “CARE” approach in the ESC guideline published in 2024. Drug therapy for atrial fibrillation is primarily aimed at preventing...…
View Post 6 min This content is machine translated MASLD/MASH Drug therapy options on the rise: spectacular evidence Over the last few decades, the incidence of steatotic liver disease has risen in parallel with the increase in obesity, diabetes and other metabolic diseases. It is recommended to screen...…
View Post 2 min This content is machine translated TREATswitzerland Register Evaluation of system therapies for AD In addition to conventional immunosuppressants, several monoclonal antibodies (biologics) and Janus kinase inhibitors (JAK-i) are now approved for the systemic treatment of atopic dermatitis (AD) in Switzerland. The primary objective...…
View Post 9 min This content is machine translated Parkinson's disease: progressive and clinically heterogeneous Individualized management of motor and non-motor symptoms Primary care providers are the central point of contact for the early detection of Parkinson’s disease, but collaboration with neurological specialists is essential. The diagnosis is still primarily made clinically....…
