This content is machine translated Crohn's disease: focus on long-term results “Top-down” approach or classic step therapy? The standard treatment of Crohn’s disease (Crohn’s disease) is based on the “step-up” strategy. However, results from the PROFILE study indicate that in newly diagnosed Crohn’s disease, early use of...…
View Post 6 min This content is machine translated Pre-acclimatization on Mount Everest Exploring the physiological limits Traditionally, a period of six to nine weeks is planned for an Everest expedition. This established practice was called into question in 2025 when five British mountaineers climbed Everest in...…
View Post 5 min This content is machine translated Sarcoidosis New options from JAKi to mTOR Despite decades of clinical experience, the treatment of sarcoidosis remains a challenge. Although established treatment strategies such as corticosteroids, methotrexate or TNF-alpha blockers are available, the options are limited, particularly...…
View Post 6 min This content is machine translated Head and neck squamous cell carcinoma Precision immunotherapy and local treatment The role of immunotherapy in the treatment of locally advanced head and neck squamous cell carcinoma (LA-HNSCC) is currently being reassessed. At the SOHC Congress 2025 in Basel, Yungan Tao...…
View Post 5 min This content is machine translated Ulcerative colitis: current evidence on anti-inflammatory therapies Remission induction and maintenance with biologics and JAK-i The most important therapeutic goal in ulcerative colitis is clinical and endoscopic remission. For moderate to severe disease activity, various options for therapy escalation are available. A non-interventional study examined...…
View Post 4 min This content is machine translated Bronchiectasis New strategies against neutrophilic inflammation While bronchiectasis has long been regarded primarily as a consequence of chronic infections, neutrophilic inflammation is increasingly coming into focus as a key driver of progression and exacerbations. This is...…
View Post 7 min This content is machine translated Orthobiologics for knee osteoarthritis PRP and hyaluronic acid injections as building blocks in a multimodal concept Conservative arthrosis therapy aims to alleviate pain and maintain mobility, whereby the measures should be individually tailored to the patient. In addition to addressing lifestyle factors, physiotherapy and physical applications...…
View Post 5 min This content is machine translated Omaveloxolone for Friedreich's Ataxia Efficacy and Safety Studied Over 6 Years Friedreich’s ataxia is associated with multisystemic manifestations such as cardiomyopathy, scoliosis, and diabetes. The progression of the disease is typically characterized by a gradual decline in neurological function and activities...…
View Post 6 min This content is machine translated Psoriasis: therapy with biologics and TYK-2-i Progress assessments based on current long-term and real-world data A broad spectrum of systemic agents is now available for the treatment of moderate to severe psoriasis. At this year’s DDG congress “Dermatology compact + practical”, various studies were presented...…
View Post 4 min This content is machine translated Hypertension: the most important facts for daily practice Early dual antihypertensive therapy is usually indicated 95% of all hypertensive patients have primary hypertension. Over the years, the classification has evolved into a more differentiated system. The current ESC guideline, for example, differentiates between hypertension, raised...…
View Post 5 min This content is machine translated Older patients with atopic dermatitis Why the Use of Biologics Is Recommended In light of demographic trends, an increase in the prevalence of atopic dermatitis is also being observed among the elderly population. Tailored treatment plans take into account a wide range...…
