This content is machine translated Advanced breast cancer Next-generation SERD therapy with promising results The results of the Phase III EMBER-3 trial of imlunestrant, a next-generation oral selective oestrogen receptor degrader (SERD) for patients with hormone receptor-positive breast cancer in ER-positive, HER2-negative advanced breast...…
View Post 6 min This content is machine translated Urticaria & urticaria-like exanthema Case studies from pediatric dermatology The lifetime prevalence of urticaria is almost 20%. Second-generation antihistamines are also recommended as first-line therapy for pediatric patients. However, pediatric patients with itchy wheals are not always suffering from...…
View Post 6 min This content is machine translated Vitiligo in children and adolescents Just don’t bury your head in the sand! This dermatosis, which is based on the destruction of melanocytes, can occur at any age – however, it usually affects 10-30 year olds and in over a third of cases...…
View Post 3 min This content is machine translated Hodgkin's lymphoma No more transplants for relapsed or refractory HL in the future? The standard treatment approach for relapsed or refractory (RR) classical Hodgkin’s lymphoma (HL) after failure of first-line treatment is second-line therapy with the aim of achieving complete remission (CR), followed...…
View Post 3 min This content is machine translated Gram-negative foot infection Not to be taken lightly Infections of wounds in the foot area are common and correct classification is sometimes a challenge. In Gram-negative foot infections, clinical findings form the backbone of the diagnosis. Local therapy...…
View Post 2 min This content is machine translated Smoldering multiple myeloma Daratumumab delays progression in smoldering multiple myeloma Smoldering multiple myeloma (SMM) is an asymptomatic premalignant precursor of active multiple myeloma (MM). Results of the presented phase III AQUILA study show that daratumumab significantly delays the progression of...…
View Post 2 min This content is machine translated Late-onset autoimmune diabetes (LADA) Type 1 adults often misdiagnosed as type 2 Type 1 diabetes can occur at any age, but is more common in children and adolescents. However, it is not yet known which people have an increased risk of developing...…
View Post 3 min This content is machine translated Post-bariatric hypoglycemia (PBH) The diagnosis is “somehow difficult” As the prevalence of obesity continues to rise worldwide, bariatric surgery remains an extremely effective measure in the treatment of severe cases. The surgical procedure results in significant weight loss,...…
View Post 8 min This content is machine translated Neurocognitive disorders in old age Depression, dementia or delirium? Depression is the most common mental illness in the 65-80 age group. However, depressive disorders are not always correctly recognized, as patients usually report non-specific somatic complaints. Dementia is not...…
View Post 2 min This content is machine translated Tirzepatide after the menopause stage Significant reduction in KG and waist circumference In the SURMOUNT program (SM), treatment with tirzepatide led to a significant and clinically meaningful reduction in body weight (BW) in overweight and obese subjects. In a post-hoc analysis, the...…
View Post 5 min This content is machine translated Type 2 diabetes and cardiovascular disease How to reduce the burden of disease and improve prognosis Type 2 diabetes is known to increase the risk of cardiovascular disease. The ADA guidelines updated in 2025 propose specific screening measures for heart failure, coronary heart disease and PAD....…
