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Dermatology and venereology

1057 posts
  • This content is machine translated Cutaneous Crohn's disease

Effective alternative to TNF inhibitors

Cutaneous Crohn’s disease (CCD ) is a granulomatous skin disease that is not associated with the gastrointestinal tract. It rarely correlates with intestinal disease and often requires separate treatment. Although...…
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  • 5 min
  • This content is machine translated Case Report

53-year-old female patient with palmoplantar keratoderma

Palmoplantar keratoderma is characterized by excessive epidermal thickening of the skin on the palms and/or plantar surfaces of the feet and can be hereditary or acquired. The spectrum of possible...…
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  • 4 min
  • This content is machine translated Psoriatic arthritis

Long-term remission also possible without DMARDs

Remission without disease-modifying antirheumatic drugs has become an ambitious goal in inflammatory rheumatic diseases. While it has been extensively studied in rheumatoid arthritis, its feasibility in psoriatic arthritis (PsA) has...…
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  • 8 min
  • This content is machine translated GPP: from molecular principles to targeted therapy

Therapeutic rationale for targeted IL-36 receptor inhibition

The progress in the diagnosis and treatment of generalized pustular psoriasis (GPP) is remarkable. GPP has developed into a clearly defined, independent, IL-36-mediated autoinflammatory disease. Today, the high chronic disease...…
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  • 4 min
  • This content is machine translated Chronic hand eczema

Topical pan-JAK-i vs. systemic retinoid: head-to-head study

Alitretinoin is currently the only systemic treatment approved for severe chronic hand eczema when patients do not respond adequately to topical corticosteroids. The topical pan-Janus kinase (JAK) inhibitor delgocitinib is...…
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  • 6 min
  • This content is machine translated Actinic keratosis

Field-directed therapy methods: what the European guideline recommends

Topically applied medications are a cornerstone of the field-directed treatment of actinic keratoses. In photodynamic therapy, a topical agent is combined with a procedural method. In cases of insufficient response,...…
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  • 6 min
  • This content is machine translated Itching in primary biliary cholangitis

When the skin becomes agony

The agonizing itching is one of the most difficult symptoms to bear in patients with primary biliary cholangitis (PBC). It can have a far greater impact on everyday life, sleep...…
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  • 2 min
  • This content is machine translated TREATswitzerland Register

Evaluation of system therapies for AD

In addition to conventional immunosuppressants, several monoclonal antibodies (biologics) and Janus kinase inhibitors (JAK-i) are now approved for the systemic treatment of atopic dermatitis (AD) in Switzerland. The primary objective...…
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  • 10 min
  • This content is machine translated Collagenoses

Scleroderma – Current recommendations for diagnosis and therapy 2025

Early detection is critical for treatment options of this multisystem disease with cutaneous involvement. Raynaud’s attacks are often in early stages and should always be further evaluated. Advances in research...…
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  • 8 min
  • This content is machine translated Atopic dermatitis

From skin barrier disorder to atopic march?

An early onset and persistent course of atopic dermatitis are the strongest predictors of atopic march. New diagnostic methods such as electrical impedance spectroscopy and the analysis of biomarkers from...…
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  • 9 min
  • This content is machine translated Psoriasis: intervening in the inflammatory cascade

Advantages of early biologic therapy and oral peptide as a beacon of hope

The question of whether early biologics treatment can have a lasting effect on the course of psoriasis is the focus of numerous research projects. The GUIDE study investigated the corresponding...…
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