This content is machine translated Small Molecules Phosphodiesterase-4 as a therapeutic target in psoriasis – an update. The oral PDE-4 inhibitor apremilast has been an established treatment option for moderate to severe chronic plaque psoriasis and psoriatic arthritis for several years. And in a phase IIb study…
View Post 10 min This content is machine translated Side effect management Immune checkpoint inhibitor associated neurological side effects. Immune checkpoint inhibitors are finding increasingly widespread use in oncology with some breakthrough success. However, the activation of the immune system also triggers a wide range of side effects. Neurological… CME-Test
View Post 4 min This content is machine translated Anxiety and sleep disorders Phytotherapeutic agent has no effect on driving ability Anxiety and sleep disorders are common and are associated with a reduced quality of life. Sedatives such as benzodiazepines have anxiolytic effects but impair driving ability. This is associated with…
View Post 6 min This content is machine translated Chronic wounds Local therapy of poorly healing, infectious wounds Pressure ulcers, diabetic foot syndrome and venous leg ulcers are the most common causes of chronic wounds and are becoming an increasingly important topic in dermatology. W.A.R and PEDIS scores…
View Post 4 min This content is machine translated Pulmonary embolism Anticoagulate hemodynamically unstable patients even on suspicion Patients with pulmonary embolism require anticoagulation for a period of at least three months. Before starting therapy, several considerations must be addressed: Which anticoagulant is the most appropriate for this…
View Post 16 min This content is machine translated Actinic keratoses Prevention and Therapy – Guideline Recommendations and Future Developments The prevalence of current actinic keratosis (AK) sufferers in the population increases with age. Depending on UV exposure, the development of AK is relevant from the age of 40. In… CME-Test
View Post 3 min This content is machine translated Heart failure SGLT-2 inhibitors – great therapeutic potential in HFrEF patients. In addition to the SGLT-2 inhibitor dapagliflozin, which was also approved by Swissmedic last July for the treatment of heart failure (HFrEF) in non-diabetics, another member of this drug class,…
View Post 3 min This content is machine translated Reflux Also of interest to the pulmonologist In Western countries, GERD (gastroesophageal reflux disease) affects approximately 20% of the population. Normally, the route leads to the gastroenterologist, but because the food pathway and the airway cross at…
View Post 12 min This content is machine translated Forensic Medicine Death certificate and then the coroner? Death is increasingly on our minds, especially in the current times, and among other things it makes us think about ethical, moral and legal issues regarding dying. Is it still… CME-Test
View Post 5 min This content is machine translated Chronic lymphocytic leukemia BTK inhibitors and other hopefuls The therapy of chronic lymphocytic leukemia (CLL) is currently undergoing rapid change. Increasingly, chemoimmunotherapy, which has been commonly used in the past, is being replaced by more targeted treatments. In…
View Post 12 min This content is machine translated Domestic violence in family practice Victims rarely confide The total number of violent crimes related to domestic violence (HG) has been steadily increasing in Switzerland since 2011. On average, one person dies every two weeks in Switzerland due… CME-Test
