This content is machine translated Rare skin diseases Darier’s disease – a hereditary keratinization disorder The disease, also known as dyskeratosis follicularis, is associated with impaired keratinization of the epidermis, hair follicles and fingernails. Histologically, Darier’s disease is characterized by marked dyskeratosis. Therapeutic options are…
View Post 8 min This content is machine translated Perioperative myocardial infarction/injury (PMI). Long-term outcomes after non-cardiac interventions. Perioperative myocardial infarction/injury (PMI) after noncardiac surgery is a common cardiac complication. A better understanding of the underlying etiology and consequences is urgently needed.
View Post 7 min This content is machine translated VTE PREDICT risk score Estimation of benefits and harms of extended anticoagulation The decision to discontinue or continue anticoagulation for venous thromboembolism (VTE) after initial treatment is challenging because individual risks for recurrence and bleeding are heterogeneous. Therefore, one study investigated the…
View Post 12 min This content is machine translated Research PTX3 contributes to trastuzumab-induced cardiac complications Trastuzumab, the first humanized monoclonal antibody targeting human epidermal growth factor receptor 2 (ERBB2/HER2), is currently used as first-line therapy for HER2(+) tumors. However, trastuzumab increases the risk of cardiac…
View Post 3 min This content is machine translated Onychomycosis New guideline summarizes current consensus recommendations Fungal nail diseases are frequent diagnoses in dermatological practice. What is recommended in terms of material collection and pathogen detection from microscopy and histology to PCR? For which degree of…
View Post 9 min This content is machine translated Validation of a new numerical model Prediction of regionalized blood flow in coronary arteries. Ischemic heart disease is the result of inadequate coronary blood flow. Direct measurement of absolute blood flow (mL/min) is possible, but has not found its way into routine clinical practice…
View Post 3 min This content is machine translated Wound care: Infection prevention and hygiene Practice-oriented guide published The Microbiology and Hygiene Working Group, established in 2019 by the Chronic Wound Initiative (ICW), has updated its consensus recommendation, Infection Prevention and Hygiene in Wound Care, with an emphasis…
View Post 4 min This content is machine translated From symptom to diagnosis Abdominal pain – Introduction Abdominal pain may be due to various pathological changes. Various diagnostic methods are used in the clarification process. Imaging techniques are particularly useful for confirming or excluding suspected diagnoses and…
View Post 6 min This content is machine translated Prevent arteriosclerosis Can exercise in early adulthood protect against atherosclerosis? Low physical fitness and muscle strength in early adulthood are risk factors for cardiovascular disease (CVD). However, it is unclear how these factors relate to subclinical atherosclerosis because of the…
View Post 5 min This content is machine translated Systemic lupus erythematosus (SLE) Anifrolumab: 3-year data confirm long-term clinical benefit New data from a long-term extension study show that anifrolumab was effective, safe, and tolerable in systemic lupus erythematosus (SLE) even in long-term use over three years [1]. Two post-hoc…
View Post 2 min This content is machine translated Geriatric dermatology: study report. Skin cancer as a leading diagnosis in elderly hospitalized dermatologic patients In view of the demographic development, the importance of skin diseases in geriatric patients is increasing in everyday practice. A study by a German research team analyzed data from patients…
