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General Internal Medicine

1995 posts
  • This content is machine translated Rare diseases: hATTR amyloidosis

What treatment options are available today?

Transthyretin-associated amyloidosis (ATTR) is hereditary (hATTR) or acquired (wATTR). In patients with unclear left ventricular hypertrophy and characteristic findings, it is recommended to investigate the presence of cardiac amyloidosis. In…
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  • 5 min
  • This content is machine translated Acute bronchitis

Pelargonium extract shortens duration of incapacity to work

Acute bronchitis is associated with considerable economic consequences due to absence from work. A meta-analysis published in 2023 investigated whether treatment with a standardized Pelargonium extract can reduce the time…
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  • 4 min
  • This content is machine translated Acute myocardial infarction and heart failure in young diabetics

Type 2 with a poor risk profile for CVD

Type 1 and type 2 diabetes differ in many ways, but both types are strongly associated with a high risk of cardiovascular complications. T2D at a young age is considered…
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  • 6 min
  • This content is machine translated Incretin-based therapies for type 2 diabetes

Evolution of therapy options continues

Incretin mimetics are an attractive treatment option, particularly for the subgroup of overweight type 2 diabetics, as they not only have glucose-lowering effects, but have also demonstrated clinical benefits in…
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  • 6 min
  • This content is machine translated COPD exacerbations

A prick for more safety

Frequent exacerbations are a key factor in the poor prognosis of COPD. Avoiding them is therefore an important goal in therapy. Vaccinations against bacterial and viral infections such as pneumococcus,…
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  • 5 min
  • This content is machine translated Antiphospholipid syndrome

The new ACR/EULAR classification criteria

Antiphospholipid syndrome (APS) is a life-threatening autoimmune disease of blood coagulation characterized by thrombophilia. In 2023, new international classification criteria were published for the first time since 2006. In view…
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  • 4 min
  • This content is machine translated Pharmacotherapy for people over 80

A case of age discrimination?

SGLT2 inhibitors and GLP1 receptor agonists have emerged as the drugs of first choice in the guidelines for type 2 diabetes. Sulfonylureas and insulin, on the other hand, were deprioritized…
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  • 3 min
  • This content is machine translated Restless Legs Syndrome

When restless legs make life difficult

Restless legs syndrome is a disorder of the nervous system that causes restlessness of movement and discomfort in the legs, which mainly occurs in the evening and at night and…
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  • 6 min
  • This content is machine translated Chronic rhinosinusitis with nasal polyposis (CRSwNP)

Criteria-driven use of biologics

Typical symptoms of chronic rhinosinusitis with nasal polyps (CRSwNP) are obstructed nasal breathing, secretions, facial pain and olfactory disturbances. If adequate therapy is not provided, there is a risk of…
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  • 5 min
  • This content is machine translated Heart failure and type 2 diabetes

SGLT-2-i now recommended for the entire LVEF spectrum

Based on data from large clinical trials, it is currently recommended that all patients with diabetes and chronic heart failure – regardless of left ventricular ejection fraction – are treated…
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  • 5 min
  • This content is machine translated Severe asthma

Check diagnosis and initiate phenotype-based therapy

In patients with inadequately controlled asthma under maximum inhalation therapy, it should be critically questioned whether the diagnosis of asthma is really present and whether all treatment measures are being…

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