This content is machine translated Smoldering multiple myeloma Daratumumab delays progression in smoldering multiple myeloma Smoldering multiple myeloma (SMM) is an asymptomatic premalignant precursor of active multiple myeloma (MM). Results of the presented phase III AQUILA study show that daratumumab significantly delays the progression of...…
View Post 5 min This content is machine translated Case Report A rare and well-hidden subcutaneous lymphoma Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is rare and has developed into a distinct entity over the last three decades. Traditionally characterized by skin lesions, in this case it presents as...…
View Post 3 min This content is machine translated Acute myeloid leukemia QuANTUM wild-type Phase 3 trial for patients with FLT3-ITD-negative AML started Acute myeloid leukemia (AML) is one of the most common forms of leukemia in adults. To date, there are no approved FLT3 inhibitors for patients with FLT3-ITD-negative AML, although sustained...…
View Post 12 min This content is machine translated Diabetic ketoacidosis Recommendations for action in practice Diabetic ketoacidosis (DKA) is an acutely life-threatening complication of diabetes mellitus that occurs predominantly in type 1 diabetes, but is also increasingly occurring in people with type 2 diabetes. A… CME-Test
View Post 5 min This content is machine translated LDL cholesterol level On the way to the (LDL-C) target Cardiovascular disease ( CVD) is the leading cause of death worldwide. Lowering the level of LDL cholesterol (LDL-C) in the blood reduces the risk of CVD such as heart attacks…
View Post 4 min This content is machine translated Diffuse large B-cell lymphoma T-cell-based therapy “off the shelf” Two types of T-cell-based therapy are available for refractory or relapsing diffuse large B-cell lymphoma (DLBCL): CAR T cells and bispecific antibodies. While CAR T cells have revolutionized individualized medicine…
View Post 4 min This content is machine translated Aplastic anemia Etiology and severity as criteria for therapy selection Aplastic anemia is associated with bone marrow hypocellularity and pancytopenia. In patients with immune-mediated severe or very severe aplastic anemia for whom bone marrow transplantation is not an option, the…
View Post 3 min This content is machine translated Medical oncology Mastering challenges, shaping innovations Interdisciplinary networking and personal exchange of experience are essential for international cooperation. Around 5500 participants took part in the DGHO in Basel. The largest congress for the specialist field in…
View Post 6 min This content is machine translated Essential thrombocythemia Risk assessment is of vital importance – a look at the data situation Essential thrombocythemia usually occurs after the age of 50, although there are also those affected under the age of 40. Various subtypes can be distinguished based on molecular genetic analyses.…
View Post 4 min This content is machine translated Immuno-oncological therapies CAR-T cell therapy for hematologic cancers Immunotherapies are now established pillars in the treatment of cancer. The principle of CAR-T cell therapy is that the body’s own T cells are programmed to destroy cancer cells through…
View Post 7 min This content is machine translated Hematology A closer look at hemato-oncological entities The latest advances in the field of hematology were the focus of this year’s annual meeting of the European Hematology Association in Madrid. Experts discussed research data on various diseases…
