This content is machine translated Endocrinology: APECED-Associated Hypoparathyroidism A parathyroid hormone analog corrected serum calcium levels Autoimmune polyendocrinopathy-candidiasis-ectodermal dysplasia (APECED), also known as autoimmune polyglandular syndrome type 1, has an estimated prevalence of 2.6–10 cases per million people and a heterogeneous clinical presentation. The classic triad...…
View Post 17 min This content is machine translated ESC Guideline Cardiovascular Diseases and Chronic Kidney Disease: What the New Guidelines Require On August 28, 2026, the European Society of Cardiology published its first independent guideline on cardiovascular disease and chronic kidney disease, developed in collaboration with the European Renal Association and...…
View Post 4 min This content is machine translated Case Study: Secondary Pseudohypoaldosteronism Severe electrolyte imbalances and nonspecific symptoms in an infant The pediatric patient was admitted to the hospital on several occasions with feeding difficulties, vomiting, severe dehydration, and electrolyte imbalances. During his second hospitalization, he was in critical condition. The...…
View Post 4 min This content is machine translated CKD and High Blood Pressure Keeping an Eye on Bidirectional Interactions Both hypertension and chronic kidney disease (CKD) are asymptomatic for long periods of time but pose serious health risks, underscoring the importance of timely screening in primary care. In this...…
View Post 3 min This content is machine translated Genetic Kidney Disease: DOUBLE PROTECT Alport The SGLT-2 inhibitor dapagliflozin as an add-on to RAS blockade The broad spectrum of therapeutic effects of SGLT-2 (sodium-glucose cotransporter-2) inhibitors includes, among other things, cardiorenal protection in patients with non-diabetic chronic kidney disease (CKD), as impressively demonstrated by large...…
View Post 5 min This content is machine translated Systemic Lupus (SLE): What Does the Diagnosis and Treatment Toolbox Have to Offer? Treat-to-Target – Consensus Recommendations for GC Tapering and the Use of DMARDs In addition to the EULAR (European Alliance of Associations for Rheumatology)/ACR (American College of Rheumatology) classification criteria, there are other validated tools that facilitate the early detection of SLE, such...…
View Post 6 min This content is machine translated C3 glomerulopathy—can its progression be halted? Iptacopan and Pegcetacoplan Open Up New Horizons To diagnose C3 glomerulopathy (C3G) and distinguish it from other membranoproliferative glomerulopathies, a kidney biopsy is required in addition to measuring the concentration of the complement protein C3 in the...…
View Post 6 min This content is machine translated CKD: Cardiorenal Benefits of nsMRA and GLP-1RA FIND-CKD and FLOW: Benefits Across Heterogeneous Patient Populations Finerenon significantly slowed the decline in kidney function in non-diabetic adults with chronic kidney disease (CKD) and also reduced the risk of cardiovascular complications —according to recently published data from...…
View Post 8 min This content is machine translated IgA Nephropathy: The Evolving Landscape of Treatment What are the most important game-changers? IgA nephropathy, also known as “Berger’s disease,” is the most common form of glomerulonephritis worldwide. It is an immune-mediated kidney disease diagnosed based on urine test results and a kidney...…
View Post 7 min This content is machine translated Lupus Nephritis – Countering the Attack on the Immune System Innovative adjunctive therapies promote renal remission Early diagnosis and treatment of lupus nephritis can be crucial for preserving kidney function. Among the adjunctive immunomodulatory therapies, two B-cell-targeted antibodies with different mechanisms of action—belimumab and obinutuzumab—are now...…
View Post 4 min This content is machine translated From symptom to diagnosis Oncology – Adrenal Mass If adrenal masses are discovered as incidental findings (incidentalomas), a pheochromocytoma should be ruled out even in asymptomatic patients. Cystic lesions of the adrenal glands are rare and usually asymptomatic....…
