This content is machine translated Type 2 diabetes and CKD: primary and secondary prevention Screening paves the way for the best possible cardiorenal protection The presence of type 2 diabetes is considered a risk factor for the development of chronic kidney disease (CKD). Simple screening measures based on blood and urine samples can detect...…
View Post 4 min This content is machine translated Diabetic nephropathy Dapagliflozin and pioglitazone are not inferior as lone fighters The treatment of diabetic nephropathy (DN) has made significant progress in the past. Nevertheless, the number of diabetic patients who ultimately develop end-stage renal disease remains high. A combination of…
View Post 12 min This content is machine translated Diabetic ketoacidosis Recommendations for action in practice Diabetic ketoacidosis (DKA) is an acutely life-threatening complication of diabetes mellitus that occurs predominantly in type 1 diabetes, but is also increasingly occurring in people with type 2 diabetes. A… CME-Test
View Post 3 min This content is machine translated Rare diseases Wolfram syndrome The term “DIDMOAD” syndrome – an acronym for the characteristic symptoms – serves as an alternative name for this autosomal recessive neurodegenerative disease, which was first described in 1938: Diabetes...…
View Post 6 min This content is machine translated Chronic kidney disease SGLT-2-i: consider for all CKD patients Targeted early detection measures and timely treatment of chronic kidney disease (CKD) are extremely important to halt progression and manage complications. The determination of albuminuria makes it possible to make...…
View Post 5 min This content is machine translated DPP4 inhibitor in adolescents with type 1 diabetes Sitagliptin add on shows renoprotective effect Children with type 1 diabetes have an increased risk of developing diabetic kidney disease (DKD). Inhibition of dipeptidyl peptidase-4 (DPP4) has positive effects on various metabolic indicators in diabetes. Egyptian…
View Post 5 min This content is machine translated Rare diseases Fanconi-Bickel syndrome Fanconi-Bickel syndrome (FBS) occurs due to variants in the SLC2A2 gene. The diagnosis of a rare genetic disease can take up to 5-6 years, even longer in low and middle…
View Post 5 min This content is machine translated Journal Club Nephrolithiasis and gout: SGLT2i could be an effective supplement Nephrolithiasis and gout are diseases with an increasing global burden and often co-occur with type 2 diabetes mellitus. SGLT2 inhibitors, which were first approved for the treatment of hyperglycemia in…
View Post 4 min This content is machine translated The endocrine basis of the cardiorenal axis New perspectives on the role of Corin In recent decades, the central role of natriuretic peptides (NPs) in the interaction between the heart and kidneys has been uncovered. These peptides, especially the atrial natriuretic peptide (ANP) and…
View Post 6 min This content is machine translated Birt-Hogg-Dubé syndrome Fibrofolliculomas as indicator lesions The vast majority of patients affected by this rare hereditary tumor syndrome develop numerous fibrofolliculomas in middle age, particularly on the face and upper body. Genetic testing is required to…
View Post 14 min This content is machine translated Kidney cancer Palliative systemic therapy for metastatic renal cell carcinoma Renal cell carcinoma (RCC) is the most common malignant disease of the kidney. There are currently no established predictive biomarkers to guide palliative therapy with checkpoint inhibitors (CPI), tyrosine kinase… CME-Test