This content is machine translated Switzerland's First PTH Replacement Therapy Palopegteriparatide for Chronic Hypoparathyroidism Chronic hypoparathyroidism is one of the few endocrine disorders for which no causal hormone replacement therapy has been available for decades. Treatment focused not on the underlying hormone deficiency, but...…
View Post 4 min This content is machine translated CKD and High Blood Pressure Keeping an Eye on Bidirectional Interactions Both hypertension and chronic kidney disease (CKD) are asymptomatic for long periods of time but pose serious health risks, underscoring the importance of timely screening in primary care. In this...…
View Post 5 min This content is machine translated Systemic Lupus (SLE): What Does the Diagnosis and Treatment Toolbox Have to Offer? Treat-to-Target – Consensus Recommendations for GC Tapering and the Use of DMARDs In addition to the EULAR (European Alliance of Associations for Rheumatology)/ACR (American College of Rheumatology) classification criteria, there are other validated tools that facilitate the early detection of SLE, such...…
View Post 18 min This content is machine translated From an antidiabetic drug to a distinct class of cardiorenal therapies The Incretin Revolution in Cardiology Within a decade, incretin mimetics have evolved from blood-sugar-lowering diabetes medications into one of the most dynamic classes of drugs in cardiovascular medicine. GLP-1 receptor agonists (GLP-1-RA) have been shown...…
View Post 8 min This content is machine translated Chronic Pruritus in Renal, Hepatic, and Biliary Tract Diseases Pooled Expertise for Targeted Evaluation and Treatment According to the International Forum for the Study of Itch (IFSI), chronic pruritus can be classified into three categories. The etiological classification of pruritus on primarily non-lesional (IFSI II) skin...…
View Post 12 min This content is machine translated Why the Finerenon Boom Is Giving Hyperkalemia Treatment New Relevance Potassium binders as enablers of RAASi optimization Renin-angiotensin-aldosterone system (RAAS) inhibitors—including mineralocorticoid receptor antagonists (MRAs)—are among the most effective tools in cardiorenal medicine. However, their benefits are often undermined in everyday clinical practice because fear of hyperkalemia...…
View Post 5 min This content is machine translated CKD in People with Type 2 Diabetes: Evidence-Based, Optimized Treatment SGLT-2 inhibitors and GLP-1 receptor agonists: significant improvement in renal outcomes Approximately 30–40% of patients with type 2 diabetes develop chronic kidney disease (CKD) over time. In “landmark” studies such as CREDENCE, DAPA-CKD, EMPA-KIDNEY, and several others, SGLT-2 (sodium-glucose-linked transporter 2)...…
View Post 4 min This content is machine translated From symptom to diagnosis Multilocular cystic renal cell carcinoma (MCRCC) MCRCC is a rare subtype of clear cell renal cell carcinoma of low malignant potential. This multilocular cystic neoplasm of the kidney presents with characteristic pathologic features and consists almost...…
View Post 5 min This content is machine translated SGLT2 inhibitors for type 2 diabetes and CKD Prediction model beats albuminuria threshold SGLT2 inhibitors also significantly reduce the risk of kidney disease progression in patients with type 2 diabetes and preserved kidney function, whereby the relative benefit is independent of albuminuria status....…
View Post 4 min This content is machine translated Incorrect type 2 diagnosis and SGLT2i led to DKA Incorrect type 2 diagnosis and SGLT2i led to DKA A patient on SGLT2 inhibitor therapy developed euglycemic diabetic ketoacidosis, which ultimately led to a diagnosis of latent autoimmune diabetes in adults (LADA). The misdiagnosis of type 2 diabetes delayed...…
View Post 5 min This content is machine translated Case study Autosomal recessive polycystic kidney disease: atypical phenotype In a 5-year-old boy with renal ultrasound findings typical of autosomal recessive polycystic kidney disease (ARPKD), numerous large liver cysts were found – atypical for this disease. Genetic analyses revealed...…
