This content is machine translated Cholangiocarcinoma Modern molecular diagnostics and targeted therapy options Cholangiocarcinoma (CCA) is one of the most aggressive tumors of the hepatobiliary system and is often only diagnosed at an advanced stage. Advances in molecular diagnostics and targeted therapy are...…
View Post 4 min This content is machine translated HER2+ early breast cancer DESTINY-Breast11 – neoadjuvant T-DXd without anthracyclines The phase III DESTINY-Breast11 trial shows that neoadjuvant trastuzumab deruxtecan (T-DXd) could provide an anthracycline-free treatment option for HER2-positive early breast cancer. The results suggest an effective and better tolerated...…
View Post 5 min This content is machine translated Mantle cell lymphoma Recurrence after BTK inhibition – prognostic factors and treatment options Mantle cell lymphoma (MCL) is a rare B-cell non-Hodgkin’s lymphoma with a markedly heterogeneous course. The spectrum ranges from indolent, slowly progressive forms to highly aggressive variants. Diagnosis and treatment...…
View Post 8 min This content is machine translated Urothelial carcinoma Immune and targeted therapy options: Evidence situation 2025/2026 The treatment of urothelial carcinoma has developed significantly in recent years. Modern immunotherapies, antibody-drug conjugates (ADCs) and targeted substances complement conventional chemotherapies and increasingly enable individualized treatment strategies. New data...…
View Post 36 min This content is machine translated Prostate and ovarian cancer Fertility preservation from gonads to genomes to genoids Ovarian and prostate cancers rely on common hormonal, genetic and inflammatory mechanisms that influence both tumor progression and gonadal reproductive function in both sexes; in addition, ovarian stem cell populations...… CME-Test
View Post 14 min This content is machine translated Cardio-oncology When the heart pays for cancer treatment Recent studies show that cardiovascular mortality can become the leading cause of death in cancer survivors over the years. New data on ICI myocarditis, landmark cardioprotection trials and the first...…
View Post 12 min This content is machine translated Prevention and early detection: breast and ovarian cancer Screening strategies, risk genetics and guideline recommendations Breast cancer is the most common cancer in women worldwide – and also the one with the greatest potential for reducing mortality through structured screening. A German long-term study presented...…
View Post 3 min This content is machine translated Neuroendocrine tumors Precision medicine in diagnostics and therapy Thanks to modern imaging and molecular characterization, neuroendocrine tumours can now be detected and classified in a much more targeted manner. New therapeutic procedures such as radioligand therapy and targeted...…
View Post 14 min This content is machine translated New approvals, current study data and ADC development Antibody-drug conjugates in gynecologic oncology Antibody-drug conjugates (ADCs) have profoundly changed gynecological oncology in a very short space of time. Within just two years, three ADCs – mirvetuximab soravtansine, tisotumab vedotin and trastuzumab deruxtecan –...…
View Post 4 min This content is machine translated Pancreatic Cancer Innovative early detection with a focus on liquid biopsy and AI The early detection of pancreatic cancer is developing rapidly: new multimodal approaches combine imaging with molecular biomarkers such as ctDNA, methylation signatures, fragmentomics and proteomics. For high-risk groups in particular,...…
View Post 22 min This content is machine translated Cervical Cancer HPV prevention, screening innovation and sentinel lymph node biopsy Cervical cancer is one of the most preventable cancers worldwide – and yet over 340,000 women die from it every year. In the period 2025/2026, several developments have fundamentally changed...… CME-Test
