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Oncology

1042 posts
  • This content is machine translated Ten years of living with Fukushima

The nuclear disaster and cancer

For 40 years, IPPNW, the group of International Physicians for the Prevention of Nuclear War, has been working for a world without nuclear threats. Ten years after the nuclear disaster…
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  • 3 min
  • This content is machine translated Advanced malignant melanoma

Adjuvant immunotherapy with nivolumab: promising long-term results

According to current study data, more than half of the patients who received adjuvant treatment with the anti-PD-1 antibody were relapse-free after four years. This is further confirmation of the…
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  • 10 min
  • This content is machine translated Side effect management

Immune checkpoint inhibitor associated neurological side effects.

Immune checkpoint inhibitors are finding increasingly widespread use in oncology with some breakthrough success. However, the activation of the immune system also triggers a wide range of side effects. Neurological…
CME-Test
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  • 7 min
  • This content is machine translated Urothelial carcinoma

The role of checkpoint inhibitors

Immunotherapy is also becoming increasingly important in the treatment of urothelial carcinoma. Checkpoint inhibitors are already being used successfully, particularly in advanced tumors. Now, potential applications of avelumab, atezolizumab and…
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  • 16 min
  • This content is machine translated Actinic keratoses

Prevention and Therapy – Guideline Recommendations and Future Developments

The prevalence of current actinic keratosis (AK) sufferers in the population increases with age. Depending on UV exposure, the development of AK is relevant from the age of 40. In…
CME-Test
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  • 2 min
  • This content is machine translated Advanced high-grade serous ovarian cancer.

HRD+ tumors: first PARP inhibitor approved for first-line maintenance therapy

As the first and only PARP inhibitor, olaparib was recently approved by swissmedic for first-line maintenance therapy in patients with advanced, HRD-positive ovarian cancer. The addition of olaparib to bevacizumab resulted…
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  • 5 min
  • This content is machine translated Prevention of non-melanocytic skin cancer (NMSC).

Nicotinamide – blockbuster among cell-protective substances

It is well known that UV radiation exposure is considered a major cause of non-melanocytic skin cancer by damaging DNA and inhibiting antitumor immunity. A reduction in intracellular ATP concentration,…
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  • 4 min
  • This content is machine translated BRAFV600E-mutated metastatic colorectal cancer (mCRC).

Evidence for additional benefit of dual blockade

An expert panel finds considerable added benefit in the dual-blockade encorafenib combined with cetuximab in the treatment of metastatic colorectal cancer with BRAFV600E mutation after prior systemic therapy. This is…
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  • 5 min
  • This content is machine translated Chronic lymphocytic leukemia

BTK inhibitors and other hopefuls

The therapy of chronic lymphocytic leukemia (CLL) is currently undergoing rapid change. Increasingly, chemoimmunotherapy, which has been commonly used in the past, is being replaced by more targeted treatments. In…
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  • 6 min
  • This content is machine translated A reportage from life

The doctor as patient

Dealing with often serious illness is the most central element of the medical profession. Their own vulnerability is usually in the background. But what if it hits you? How does…
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  • 2 min
  • This content is machine translated Non-small cell lung cancer with EGRF mutation.

New approval for osimertinib for adjuvant therapy

Following convincing results from the Phase III ADAURA study, the indication for osimertinib was expanded in Switzerland. Thus, the drug may now also be used for adjuvant therapy in early-stage…

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