This content is machine translated Acute lymphoblastic leukemia Addition of blinatumomab to chemotherapy improves survival in children Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Children with newly diagnosed B-cell acute lymphoblastic leukemia (B-ALL) with standard risk (SR) have a high survival rate when treated...…
View Post 3 min This content is machine translated Advanced breast cancer Next-generation SERD therapy with promising results The results of the Phase III EMBER-3 trial of imlunestrant, a next-generation oral selective oestrogen receptor degrader (SERD) for patients with hormone receptor-positive breast cancer in ER-positive, HER2-negative advanced breast...…
View Post 3 min This content is machine translated Hodgkin's lymphoma No more transplants for relapsed or refractory HL in the future? The standard treatment approach for relapsed or refractory (RR) classical Hodgkin’s lymphoma (HL) after failure of first-line treatment is second-line therapy with the aim of achieving complete remission (CR), followed...…
View Post 2 min This content is machine translated Smoldering multiple myeloma Daratumumab delays progression in smoldering multiple myeloma Smoldering multiple myeloma (SMM) is an asymptomatic premalignant precursor of active multiple myeloma (MM). Results of the presented phase III AQUILA study show that daratumumab significantly delays the progression of...…
View Post 5 min This content is machine translated Case Report A rare and well-hidden subcutaneous lymphoma Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is rare and has developed into a distinct entity over the last three decades. Traditionally characterized by skin lesions, in this case it presents as...…
View Post 4 min This content is machine translated From symptom to diagnosis Abdominal pain – liver metastases Contrast-enhanced imaging examinations have a high sensitivity and specificity for the detection of liver metastases, whereby sonographic as well as computer and magnetic resonance imaging examinations can be used. The...…
View Post 3 min This content is machine translated Small cell lung carcinoma Durvalumab approved as first immunotherapy for patients with LS-SCLC Durvalumab has been approved as a monotherapy in Switzerland for the treatment of adult patients with unresectable small cell lung cancer (LS-SCLC, limited-stage small cell lung cancer) whose disease has...…
View Post 3 min This content is machine translated Follicular lymphoma Addition of tafasitamab significantly improves progression-free survival The results of the phase 3 study (inMIND) indicate a new treatment option for relapsed or refractory follicular lymphoma: The addition of tafasitamab to lenalidomide and rituximab significantly prolonged progression-free...…
View Post 3 min This content is machine translated Acute myeloid leukemia QuANTUM wild-type Phase 3 trial for patients with FLT3-ITD-negative AML started Acute myeloid leukemia (AML) is one of the most common forms of leukemia in adults. To date, there are no approved FLT3 inhibitors for patients with FLT3-ITD-negative AML, although sustained...…
View Post 3 min This content is machine translated Non-small cell lung cancer Management of locally advanced NSCLC – where are we heading? Lung cancer is the second most common and deadliest type of cancer worldwide. Clinically, non-small cell lung cancer (NSCLC) is the most common pathologic form of lung cancer; approximately one-third…
View Post 3 min This content is machine translated Melanoma early detection New study on tumor-specific antibodies At this year’s congress of the European Academy of Dermatology and Venereology (EADV), an innovative research paper was presented that used a promising methodology of tumor-specific profiling to detect antibodies…
