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Pharmacology and toxicology

297 posts
  • Education
  • Geriatrics
  • Neurology
  • Pharmacology and toxicology
  • RX
  • Studies

Opicapon: double benefit for motor function and sleep in Parkinson’s disease

Sleep disorders are among the most common non-motor Parkinson’s symptoms. The targeted treatment of sleep disorders is an important part of Parkinson’s therapy and can significantly improve quality of life....…
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  • 9 min
  • This content is machine translated Parkinson's disease: progressive and clinically heterogeneous

Individualized management of motor and non-motor symptoms

Primary care providers are the central point of contact for the early detection of Parkinson’s disease, but collaboration with neurological specialists is essential. The diagnosis is still primarily made clinically....…
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  • 5 min
  • This content is machine translated Multiple sclerosis

Avoiding the nocebo trap with natalizumab biosimilars

Monoclonal antibodies such as natalizumab are indispensable for multiple sclerosis therapy. A first recently approved biosimilar is clinically equivalent, as studies have shown. Nevertheless, reservations are widespread in practice. Patients...…
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  • 5 min
  • This content is machine translated Antithymocyte globulin in children with T1D

Old medicine, new hope

The well-known immunomodulatory drug antithymocyte globulin (ATG) can effectively inhibit the progression of type 1 diabetes (T1D) in young patients at low doses, while at the same time having a...…
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  • 3 min
  • This content is machine translated Development of a quintuple agonist

New strategy in the fight against obesity and T2D

The treatment of obesity and type 2 diabetes is increasingly shifting to newer incretin drugs, including GLP1 receptor agonists (single agonists such as semaglutide) and GIP- and GLP1-RA (dual agonists...…
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  • 6 min
  • This content is machine translated Obesity in the family practice

Aim for realistic goals and avoid apportioning blame

Morbid obesity is a significant health risk factor and its prevalence has increased in many industrialized countries in recent years. The principles of weight reduction have hardly changed over the...…
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  • 9 min
  • This content is machine translated Psoriasis: intervening in the inflammatory cascade

Advantages of early biologic therapy and oral peptide as a beacon of hope

The question of whether early biologics treatment can have a lasting effect on the course of psoriasis is the focus of numerous research projects. The GUIDE study investigated the corresponding...…
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  • 4 min
  • This content is machine translated Bipolar disorder, anxiety disorder, depression

Lurasidone as monotherapy for bipolar I depression with anxiety symptoms

Comorbid anxiety is common in patients with bipolar disorder. This comorbidity is associated with increased disease severity and poorer treatment response. A study with lurasidone 20-60 mg/day showed significant efficacy...…
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  • 4 min
  • This content is machine translated GLP1-RA therapy

Improvement in either weight or HbA1c – but never both

Numerous studies show that glucagon-like peptide-1 receptor agonists (GLP1-RA) can significantly reduce the risk of diabetes-related complications and also reduce mortality. Despite their proven efficacy in trial designs, patient response...…
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  • 6 min
  • This content is machine translated Suicide

Dealing with trauma after suicide loss: What do bereaved people experience as effective?

Every year, over 100 million people around the world are affected by suicide. Survivors often experience long-lasting, severe trauma and have an increased risk of mental illness and suicidal thoughts...…
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  • 6 min
  • This content is machine translated Galenic systems

Advantages of topical pharmacotherapy – Update 2025

Topical pharmacotherapies offer the unique advantage that the products are applied directly to the diseased skin, resulting in local, distinctly direct contact between the product and the affected skin. The...…
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