Education Geriatrics Neurology Pharmacology and toxicology RX Studies Opicapon: double benefit for motor function and sleep in Parkinson’s disease Sleep disorders are among the most common non-motor Parkinson’s symptoms. The targeted treatment of sleep disorders is an important part of Parkinson’s therapy and can significantly improve quality of life....…
View Post 9 min This content is machine translated Parkinson's disease: progressive and clinically heterogeneous Individualized management of motor and non-motor symptoms Primary care providers are the central point of contact for the early detection of Parkinson’s disease, but collaboration with neurological specialists is essential. The diagnosis is still primarily made clinically....…
View Post 5 min This content is machine translated Multiple sclerosis Avoiding the nocebo trap with natalizumab biosimilars Monoclonal antibodies such as natalizumab are indispensable for multiple sclerosis therapy. A first recently approved biosimilar is clinically equivalent, as studies have shown. Nevertheless, reservations are widespread in practice. Patients...…
View Post 5 min This content is machine translated Antithymocyte globulin in children with T1D Old medicine, new hope The well-known immunomodulatory drug antithymocyte globulin (ATG) can effectively inhibit the progression of type 1 diabetes (T1D) in young patients at low doses, while at the same time having a...…
View Post 3 min This content is machine translated Development of a quintuple agonist New strategy in the fight against obesity and T2D The treatment of obesity and type 2 diabetes is increasingly shifting to newer incretin drugs, including GLP1 receptor agonists (single agonists such as semaglutide) and GIP- and GLP1-RA (dual agonists...…
View Post 6 min This content is machine translated Obesity in the family practice Aim for realistic goals and avoid apportioning blame Morbid obesity is a significant health risk factor and its prevalence has increased in many industrialized countries in recent years. The principles of weight reduction have hardly changed over the...…
View Post 9 min This content is machine translated Psoriasis: intervening in the inflammatory cascade Advantages of early biologic therapy and oral peptide as a beacon of hope The question of whether early biologics treatment can have a lasting effect on the course of psoriasis is the focus of numerous research projects. The GUIDE study investigated the corresponding...…
View Post 4 min This content is machine translated Bipolar disorder, anxiety disorder, depression Lurasidone as monotherapy for bipolar I depression with anxiety symptoms Comorbid anxiety is common in patients with bipolar disorder. This comorbidity is associated with increased disease severity and poorer treatment response. A study with lurasidone 20-60 mg/day showed significant efficacy...…
View Post 4 min This content is machine translated GLP1-RA therapy Improvement in either weight or HbA1c – but never both Numerous studies show that glucagon-like peptide-1 receptor agonists (GLP1-RA) can significantly reduce the risk of diabetes-related complications and also reduce mortality. Despite their proven efficacy in trial designs, patient response...…
View Post 6 min This content is machine translated Suicide Dealing with trauma after suicide loss: What do bereaved people experience as effective? Every year, over 100 million people around the world are affected by suicide. Survivors often experience long-lasting, severe trauma and have an increased risk of mental illness and suicidal thoughts...…
View Post 6 min This content is machine translated Galenic systems Advantages of topical pharmacotherapy – Update 2025 Topical pharmacotherapies offer the unique advantage that the products are applied directly to the diseased skin, resulting in local, distinctly direct contact between the product and the affected skin. The...… CME-Test