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Pharmacology and toxicology

373 posts
  • This content is machine translated Epidermolysis bullosa

Promoting Wound Healing with Gene Therapies and Birch Bark Extract

Epidermolysis bullosa (EB) requires an interdisciplinary management approach tailored to the diagnosed EB subtype. Recently, new therapeutic approaches have been approved to improve symptomatic treatment. While a gel formulation containing...…
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  • 3 min
  • This content is machine translated Psoriasis Research: What's in the Pipeline?

Highly selective oral TYK inhibitors in Phase III

Envudeucitinib and Zasocitinib are oral, allosteric tyrosine kinase 2 (TYK2) inhibitors currently being evaluated in clinical trials for plaque psoriasis. The interim results presented during the Late-Breaking Research sessions at...…
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  • 3 min
  • This content is machine translated Adherence and management in asthma and COPD

Better to listen to the pharmacist

Pharmaceutical care has become an important part of the management of asthma and chronic obstructive pulmonary disease (COPD). There is evidence for its role in improving adherence, optimizing pharmacotherapy and...…
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  • 4 min
  • This content is machine translated Disorders of the Gut-Brain Interaction

Peppermint-Caraway Oil Supplement Proves Effective in Phase IV Trial

In primary care , disorders of the gut-brain axis—also known as functional gastrointestinal disorders—are very common. Herbal remedies, such as a proprietary combination of peppermint oil (Mentha × piperita L.)...…
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  • 5 min
  • This content is machine translated Gepante for Migraines

Relief from pain, symptoms, and improved functional ability—both acute and preventive

Migraine management goes beyond acute symptom control and may also include preventive strategies for patients with a significant disease burden. Although triptans remain the recommended first-line treatment for acute migraine,...…
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  • 12 min
  • This content is machine translated SURPASS-CVOT

Tirzepatide versus Dulaglutide in T2D with ASCVD

GLP-1 receptor agonists have established themselves in recent years as a class of drugs with cardiovascular protective effects in type 2 diabetes. For dulaglutide, the 2019 REWIND study showed that...…
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  • 5 min
  • This content is machine translated Acute ischemic stroke

Alteplase and Tenecteplase Are on the Same Level

In acute ischemic stroke (AIS), rapid reperfusion therapy is a clinical priority. Although alteplase has been the standard thrombolytic agent for many years, its short half-life requires administration as a...…
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  • 13 min
  • This content is machine translated Planning a Family, Pregnancy, and Breastfeeding

Update on Anti-Rheumatic Medications

The 2024 EULAR recommendations on the use of antirheumatic medications during reproduction, pregnancy, and breastfeeding replace the previous recommendations from 2016. During this period, studies on the safety of biologics...…
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  • 8 min
  • This content is machine translated Case study

Guillain-Barré syndrome with a fulminant course

A 38-year-old male patient experienced a transient loss of all brainstem reflexes as part of an unusual course of Guillain-Barré syndrome, which, despite preserved cortical functions, resembled a coma or...…
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  • 12 min
  • This content is machine translated The Brain and the Motivation to Eat

Why is it so hard to lose weight?

Obesity is the most common chronic disease in Western societies, with serious metabolic, cardiovascular, and psychosocial consequences. The therapeutic landscape has changed fundamentally: new-generation GLP-1 agonists achieve weight loss that,...…
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  • 12 min
  • This content is machine translated Global Recommendation, Swissmedic Approval, and SL Limitation

WHO Guidelines on GLP-1 for Obesity

With the guideline published on December 1, 2025, the World Health Organization has, for the first time, issued a globally applicable recommendation on the pharmacological management of obesity in adults....…

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