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Pharmacology and toxicology

358 posts
  • This content is machine translated Gepante for Migraines

Relief from pain, symptoms, and improved functional ability—both acute and preventive

Migraine management goes beyond acute symptom control and may also include preventive strategies for patients with a significant disease burden. Although triptans remain the recommended first-line treatment for acute migraine,...…
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  • 12 min
  • This content is machine translated SURPASS-CVOT

Tirzepatide versus Dulaglutide in T2D with ASCVD

GLP-1 receptor agonists have established themselves in recent years as a class of drugs with cardiovascular protective effects in type 2 diabetes. For dulaglutide, the 2019 REWIND study showed that...…
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  • 5 min
  • This content is machine translated Acute ischemic stroke

Alteplase and Tenecteplase Are on the Same Level

In acute ischemic stroke (AIS), rapid reperfusion therapy is a clinical priority. Although alteplase has been the standard thrombolytic agent for many years, its short half-life requires administration as a...…
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  • 13 min
  • This content is machine translated Planning a Family, Pregnancy, and Breastfeeding

Update on Anti-Rheumatic Medications

The 2024 EULAR recommendations on the use of antirheumatic medications during reproduction, pregnancy, and breastfeeding replace the previous recommendations from 2016. During this period, studies on the safety of biologics...…
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  • 8 min
  • This content is machine translated Case study

Guillain-Barré syndrome with a fulminant course

A 38-year-old male patient experienced a transient loss of all brainstem reflexes as part of an unusual course of Guillain-Barré syndrome, which, despite preserved cortical functions, resembled a coma or...…
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  • 12 min
  • This content is machine translated The Brain and the Motivation to Eat

Why is it so hard to lose weight?

Obesity is the most common chronic disease in Western societies, with serious metabolic, cardiovascular, and psychosocial consequences. The therapeutic landscape has changed fundamentally: new-generation GLP-1 agonists achieve weight loss that,...…
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  • 12 min
  • This content is machine translated Global Recommendation, Swissmedic Approval, and SL Limitation

WHO Guidelines on GLP-1 for Obesity

With the guideline published on December 1, 2025, the World Health Organization has, for the first time, issued a globally applicable recommendation on the pharmacological management of obesity in adults....…
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  • 3 min
  • This content is machine translated Tinea capitis: Current Guidelines and Recommendations

What should be kept in mind when treating adult patients?

Tinea capitis is less common in adults, but its incidence is on the rise. From a diagnostic perspective, one should be on the lookout for pathogens that are rather atypical...…
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  • 5 min
  • This content is machine translated Viloxazine for ADHD

A non-stimulating option—but with limited evidence

ADHD affects about 5–7% of children and adolescents and 2–5% of adults. Although it is generally considered a childhood disorder, symptoms persist into adulthood for the majority of those affected....…
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  • 6 min
  • This content is machine translated Schizophrenia in the early-onset stage

Which antipsychotic should be used for treatment-naive patients?

Schizophrenia often develops during adolescence or early adulthood. Neurocognitive deficits frequently occur before or during the first psychotic episode and are closely associated with poorer functional outcomes. However, the effects...…
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  • 6 min
  • This content is machine translated Psoriasis: therapy with biologics and TYK-2-i

Progress assessments based on current long-term and real-world data

A broad spectrum of systemic agents is now available for the treatment of moderate to severe psoriasis. At this year’s DDG congress “Dermatology compact + practical”, various studies were presented...…

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