This content is machine translated Phytotherapy for depression Low risk of interaction with low-hyperforin St. John’s wort St. John’s wort extracts are proven for the treatment of depressive disorders. However, some preparations, by inducing CYP3A4 and P-glycoprotein (ABCB1), lower the plasma levels of other drugs and impair…
View Post 4 min This content is machine translated Drug reactions From toots and bubbles anaphylaxis The lethality to drug reactions is 10%. Drug allergies and anaphylaxis thus form a complex of topics that must be dealt with urgently in clinics and practices, as the consequences…
View Post 3 min This content is machine translated Therapeutic Drug Monitoring For which psychotropic drugs are blood level controls useful? Determining blood levels of medications is not only mandatory for some psychotropic drugs, but overall can be very helpful in providing effective therapy. For which preparations may therapeutic drug monitoring…
View Post 2 min This content is machine translated Rhinovirus infection Fight off acute respiratory infections naturally through immune stimulation Colds are caused by rhinoviruses in 70% of cases. Typically, the disease lasts 10 to 14 days and numerous treatment options are not very effective. Patients with asthma or COPD…
View Post 9 min This content is machine translated New in the treatment of schizophrenia Similarities and differences among partial dopamine agonists. Antipsychotics are the mainstay of acute and long-term treatment for schizophrenic disorders. The earlier antipsychotic treatment begins, the greater the chance of controlling or stopping the progression of psychosis.
View Post 2 min This content is machine translated Application for approval Alzheimer’s drug to be submitted for approval After consultation with the U.S. Food and Drug Administration (FDA), the manufacturer Biogen plans to submit aducanumab for approval. The Phase 3 EMERGE study met its primary endpoint and demonstrated…
View Post 7 min This content is machine translated Special case migraine Do not take headaches in children lightly Headaches in children are often underestimated, but occur frequently with a prevalence of 79%. Due to genetic predisposition and functional impairment already from (pre-)school age, migraine is the most important.…
View Post 17 min This content is machine translated Migraine prophylaxis with medication Challenge and opportunity In the case of frequent headaches, prophylactic medication may be useful. What medications are available and what is the evidence for their efficacy?
View Post 9 min This content is machine translated Warning signs for drug allergies Hypersensitivity to drugs – main forms and warning signs Severe drug allergies can be potentially life-threatening, so early detection and treatment is very important. In many cases, these are rather harmless exanthems. However, in 2-5% of cases, these are…
View Post 12 min This content is machine translated Drug Safety Drug interactions in oncology Drugs with a narrow therapeutic range, such as those frequently used in oncology, require a basic knowledge of possible interactions with other preparations. Pharmacodynamics and pharmacokinetics should not be foreign…
View Post 5 min This content is machine translated Rational use of antidepressants First wait and see, then intervene with medication Antidepressants are prescribed too often – contrary to the study evidence, which attests only low efficacy of the commonly used agents in mild depressive episodes, and contrary to the guideline…
