This content is machine translated Severe asthma Anti-IL-5/-5Rα biologics impress in the real world Three biologics targeting interleukin 5 (IL-5) or its receptor (IL-5Rα) are approved for use in patients with severe asthma. In a meta-analysis, Greek scientists have now investigated the clinical response...…
View Post 4 min This content is machine translated Chronic obstructive pulmonary disease Polygenic risk score can help identify COPD Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death in patients worldwide and yet often goes undiagnosed. Although genetic risk plays a significant role in susceptibility...…
View Post 5 min This content is machine translated Bronchiectasis and Pseudomonas aeruginosa infection Statistically significant reduction in the frequency of exacerbations A chronic lung infection with Pseudomonas aeruginosa is associated with an increased exacerbation and mortality rate in people affected by bronchiectasis. Inhaled antibiotics are frequently used in clinical practice to...…
View Post 5 min This content is machine translated Journal Club Case-control study on post-Covid syndrome A prospective, multicenter case-control study published in PLoS Medicine in 2025 described the frequency and clinical characteristics of patients with a protracted post-Covid course and searched for risk factors for...…
View Post 9 min This content is machine translated Rare diseases: Marfan syndrome Hereditary connective tissue disease with a vascular component Even though targeted genetic tests are now available, the diagnosis of Marfan syndrome is still mainly based on specific clinical criteria, in particular the revised Ghent classification. The broad phenotypic...…
View Post 4 min This content is machine translated New prognostic indicator for idiopathic pulmonary fibrosis Low BAR allows IPF patients to live longer Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fatal and age-related interstitial lung disease whose etiology and pathogenesis are still largely unknown. It is important to identify IPF patients at...…
View Post 3 min This content is machine translated Small cell lung carcinoma Durvalumab approved as first immunotherapy for patients with LS-SCLC Durvalumab has been approved as a monotherapy in Switzerland for the treatment of adult patients with unresectable small cell lung cancer (LS-SCLC, limited-stage small cell lung cancer) whose disease has...…
View Post 7 min This content is machine translated Respiratory infections in children In which cases is antibiotic treatment obsolete? Nowadays, the motto is that antibiotics should be carefully considered. Although true scarlet fever, for example, requires antibiotic treatment, many other respiratory diseases may not require it. In addition to...…
View Post 5 min This content is machine translated Avian influenza in humans Respiratory complaints more likely with chickens than with cows In recent years, more and more infections with the H5N1 influenza A virus have been detected in mammals. Humans are also at risk, and therefore fear of this highly pathogenic...…
View Post 3 min This content is machine translated COPD therapy Package of measures to combat symptom complexes – an update In COPD, dual bronchodilation (LAMA/LABA) is generally considered the standard of care. If patients are prone to exacerbations, the addition of inhaled steroids (ICS) may be useful. But what about...…
View Post 5 min This content is machine translated Community-acquired pneumonia Prospective study in primary care Community-acquired pneumonia is one of the most common infectious diseases with high mortality and morbidity worldwide. In a study in France, clinical and microbiological characteristics of patients with radiologically confirmed...…
