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5976 posts
  • This content is machine translated Hidradenitis suppurativa

Deciphering inflammatory pathways as the basis for new therapeutic approaches

Hidradenitis suppurativa (HS) has a multifactorial etiopathogenesis and is associated with high impairment of quality of life. Empirical findings of increased expression of inflammatory cytokines suggest an immunologic genesis of…
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  • 15 min
  • This content is machine translated Therapy of venous occlusions

Endovascular interventions – option for patients with more pronounced symptoms

Deep vein thrombosis develops in 1/1000 inhabitants of Western Europe per year. In the acute phase, it is critical to prevent the complication of pulmonary artery embolism. This is now…
CME-Test
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  • 3 min
  • This content is machine translated Hypertension

Uncontrolled hypertension in the elderly: dose increase or another drug?

If the target blood pressure is not achieved, there are two approaches to intensify antihypertensive treatment: adding a new drug or maximizing the dose. A large-scale cohort study involving researchers from…
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  • 3 min
  • This content is machine translated Dyslipidemia

Effective lipid management – lipid apheresis as a last resort?

Current European guidelines advocate strict LDL-C lowering to prevent cardiovascular disease. Statins, which can significantly lower both total and LDL cholesterol, play a central role. In addition, PCSK9 inhibitors achieve…
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  • 12 min
  • This content is machine translated Malignant melanoma

Adjuvant Therapy: State of the Art

The annual incidence of malignant melanoma has steadily increased over the past 40 years. While the prognosis is good in the early stages, it worsens as the tumor stage increases.…
CME-Test
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  • 11 min
  • This content is machine translated Therapy of rheumatoid arthritis

Long-term safety for RA patients under JAK inhibition

The treatment of rheumatoid arthritis (RA) has made great progress over the past 20 years. This relates both to the range of drugs available and to developments in terms of…
CME-Test
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  • 6 min
  • This content is machine translated Valérie Krafft, Executive Director of the Rheumatism League Switzerland:

“Rheumatic diseases still meet with a lot of misunderstanding from the public”

The Swiss Rheumatism League has been working for people with rheumatism since 1958. In an interview, Executive Director Valérie Krafft explains how the non-profit organization supports those affected, why the…
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  • 8 min
  • This content is machine translated Mepolizumab as an add-on therapeutic for severe CRSwNP.

Symptomatic improvement with good tolerability

Approximately 2-4% of the general population is affected by chronic rhinosinusitis with nasal polyps (CRSwNP) [1]. Treatment options were very limited for a long time, but since the approval of…
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  • 3 min
  • This content is machine translated Fatty liver associated diseases

Regular exercise can protect

Exercise not only trains the muscles, but can also prevent the development of fatty liver. A new study by the German Center for Diabetes Research (DZD), Helmholtz Munich and the…
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  • 4 min
  • This content is machine translated Psoriatic arthritis (PsA)

Guselkumab in joint involvement – successful interim results

Long-term data from the pivotal DISCOVER-2 study show that treatment with guselkumab resulted in sustained improvements in joint and skin symptoms and functional capacity over a two-year period in biologic-naïve…
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  • 15 min
  • This content is machine translated Asthma therapy

The mild bronchial asthma

Bronchial asthma is a heterogeneous, multifactorial disease characterized by chronic airway inflammation and bronchial hyperresponsiveness. Not only the symptomatology, but also the airway obstruction is variable in time course and…

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