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5976 posts
  • This content is machine translated Tau antibodies against neurodegenerative diseases

New findings from global PSP clinical trial

Progressive Supranuclear Gaze Palsy (PSP) is a chronic progressive neurodegene-rative disease which, like Alzheimer’s disease, is one of the so-called tauopathies. To date, there is no causal treatment for these…
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  • 5 min
  • This content is machine translated Diabetic nephropathy

SGLT-2 inhibitor protects heart and kidney also in the real-world setting

Type 2 diabetes mellitus (T2DM) significantly increases the risk of cardiovascular and renal diseases [1, 2]. However, SGLT-2 inhibitors not only lower blood glucose levels but also have cardio- and…
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  • 7 min
  • This content is machine translated Testosterone

Testosterone substitution in the older man: for whom, when and how?

Hypogonadism is a clinical syndrome in which dysfunction in the hypothalamic-pituitary-gonadal axis results in decreased production of testosterone with clinical symptoms of testosterone deficiency. When should substitution take place?
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  • 3 min
  • This content is machine translated Advanced stage malignant melanoma

Advanced stage malignant melanoma

The use of targeted oncologics and immunotherapeutics has revolutionized the treatment of black skin cancer in recent years. However, the optimal therapeutic sequence remains unclear even today. A study analysis…
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  • 5 min
  • This content is machine translated Urinary tract infections

Antibiotic resistance endangers therapeutic success

Antibiotic resistance is an increasing global problem with significant consequences for the healthcare system. While antibiotics are indicated for complicated UTI, treatment without antibiotics may be considered for uncomplicated cystitis.…
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  • 9 min
  • This content is machine translated Diaper dermatitis practical

Multifactorial causes, diverse symptoms

Diaper dermatitis is a common condition in infants and incontinent persons, which is directly related to the wearing of a diaper. It heals without complications in most cases. The symptoms…
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  • 10 min
  • This content is machine translated Visceral Surgery Update - Part 1

Upper gastrointestinal tract and COVID-19 complications.

Approximately 60 per 1000 population undergo abdominal surgery annually. The majority of patients are initially evaluated and triaged in the primary care physician’s office. Visceral surgery is also constantly evolving,…
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  • 2 min
  • This content is machine translated Circular hair loss

Antihistamines as an add-on for alopecia arata?

In contrast to androgenetic alopecia, circular hair loss often occurs in childhood or adolescence. In a recent study published in the Journal of the American Academy of Dermatology, antihistamines combined…
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  • 7 min
  • This content is machine translated Unipolar depression

St. John’s wort is a proven traditional therapy option

In particular, the use of standardized St. John’s wort preparations has been shown to be effective for mild to moderate depressive symptoms, both for induction therapy and relapse prophylaxis. Based…
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  • 7 min
  • This content is machine translated Gastrointestinal stromal tumors

Portrait of a multifaceted disease

With the introduction of the new active ingredient avapritinib for the targeted treatment of gastrointestinal stromal tumors into the German market, this clinical picture is once again coming more into…
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  • 3 min
  • This content is machine translated Schizophrenia

Therapy management up to date: What’s new?

The earlier and better schizophrenia is treated, the higher the chances of a mild course with only rare acute phases. Modern therapy is therefore built on the pillars of pharmacotherapy,…

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