This content is machine translated Tau antibodies against neurodegenerative diseases New findings from global PSP clinical trial Progressive Supranuclear Gaze Palsy (PSP) is a chronic progressive neurodegene-rative disease which, like Alzheimer’s disease, is one of the so-called tauopathies. To date, there is no causal treatment for these…
View Post 5 min This content is machine translated Diabetic nephropathy SGLT-2 inhibitor protects heart and kidney also in the real-world setting Type 2 diabetes mellitus (T2DM) significantly increases the risk of cardiovascular and renal diseases [1, 2]. However, SGLT-2 inhibitors not only lower blood glucose levels but also have cardio- and…
View Post 7 min This content is machine translated Testosterone Testosterone substitution in the older man: for whom, when and how? Hypogonadism is a clinical syndrome in which dysfunction in the hypothalamic-pituitary-gonadal axis results in decreased production of testosterone with clinical symptoms of testosterone deficiency. When should substitution take place?
View Post 3 min This content is machine translated Advanced stage malignant melanoma Advanced stage malignant melanoma The use of targeted oncologics and immunotherapeutics has revolutionized the treatment of black skin cancer in recent years. However, the optimal therapeutic sequence remains unclear even today. A study analysis…
View Post 5 min This content is machine translated Urinary tract infections Antibiotic resistance endangers therapeutic success Antibiotic resistance is an increasing global problem with significant consequences for the healthcare system. While antibiotics are indicated for complicated UTI, treatment without antibiotics may be considered for uncomplicated cystitis.…
View Post 9 min This content is machine translated Diaper dermatitis practical Multifactorial causes, diverse symptoms Diaper dermatitis is a common condition in infants and incontinent persons, which is directly related to the wearing of a diaper. It heals without complications in most cases. The symptoms…
View Post 10 min This content is machine translated Visceral Surgery Update - Part 1 Upper gastrointestinal tract and COVID-19 complications. Approximately 60 per 1000 population undergo abdominal surgery annually. The majority of patients are initially evaluated and triaged in the primary care physician’s office. Visceral surgery is also constantly evolving,…
View Post 2 min This content is machine translated Circular hair loss Antihistamines as an add-on for alopecia arata? In contrast to androgenetic alopecia, circular hair loss often occurs in childhood or adolescence. In a recent study published in the Journal of the American Academy of Dermatology, antihistamines combined…
View Post 7 min This content is machine translated Unipolar depression St. John’s wort is a proven traditional therapy option In particular, the use of standardized St. John’s wort preparations has been shown to be effective for mild to moderate depressive symptoms, both for induction therapy and relapse prophylaxis. Based…
View Post 7 min This content is machine translated Gastrointestinal stromal tumors Portrait of a multifaceted disease With the introduction of the new active ingredient avapritinib for the targeted treatment of gastrointestinal stromal tumors into the German market, this clinical picture is once again coming more into…
View Post 3 min This content is machine translated Schizophrenia Therapy management up to date: What’s new? The earlier and better schizophrenia is treated, the higher the chances of a mild course with only rare acute phases. Modern therapy is therefore built on the pillars of pharmacotherapy,…