This content is machine translated HSP90 inhibition A new therapeutic approach for breast cancer In an initial phase II study in metastatic breast cancer, the HSP90 inhibitor ganetespib has shown promising antitumor activity in HER2-positive and triple-negative breast cancer (TNBC). Due to the favorable…
View Post 6 min This content is machine translated Actinic keratosis Early treatment is indicated Actinic or solar keratoses represent in situ squamous cell carcinomas of the skin and are one of the more common dermatoses in daily practice. On the one hand, it is…
View Post 2 min This content is machine translated German-speaking European School of Oncology in St. Gallen The pros and cons of antiangiogenic therapy in first-line treatment. At a DESO advanced training course in St. Gallen, Prof. Volker Heinemann, MD, Munich, and Prof. Werner Scheithauer, MD, Vienna, led a discussion on the use of first-line antiangiogenic therapies.…
View Post 3 min This content is machine translated 2nd EORTC St. Gallen Gastrointestinal Cancer Conference 2014 VEGF inhibition in metastatic colorectal cancer. The use of the VEGF inhibitor bevacizumab improves the outcome of patients with metastatic colorectal cancer regardless of the chemotherapy chosen. Recent data suggest that the duration of VEGF inhibition…
View Post 8 min This content is machine translated Advanced training Hautnah Guidelines – what to consider for diagnostics? In malignant melanoma, some new findings on prognostic factors and risks have been published recently. The changed guidelines bring some innovations in everyday life and aim at a most accurate…
View Post 10 min This content is machine translated Skin surgery Tips and tricks for practice The majority of simple surgical procedures on the skin organ can be easily performed in the office. However, as with any surgical procedure, a clear indication and selection of the…
View Post 4 min This content is machine translated Breast Cancer How should action be taken without accurate study results? What is the evidence for primary tumor and metastasis in breast carcinoma? Are there treatment options that will not harm the child if a pregnant woman is found to have…
View Post 4 min This content is machine translated Effects of physical activities on the skin Skin and sport Just over 70% of the Swiss population engage in sports at least occasionally. In addition to general fitness training, this mainly involves endurance sports such as jogging, cycling or swimming.…
View Post 4 min This content is machine translated Six year old boy with local skin lesion Two knots for the surgeon? Case report: For three to four months, this six-year-old boy developed two skin-colored nodules in the abdominal region, which increased significantly in size during the course.
View Post 8 min This content is machine translated New therapies Progress in metastatic malignant melanoma New insights in tumor biology and immunology as well as in molecular pathology have rapidly driven the development of immunomodulatory antibodies and so-called “targeted” therapeutics [1]. This makes the therapy…
View Post 3 min This content is machine translated News on melanoma therapy at ASCO 2014 How do immunotherapies work in combination and in the adjuvant setting? In the course of this year’s ASCO congress in Chicago at the beginning of June, new results of the phase Ib study on the combination of PD1 and CTLA4 inhibition…
