This content is machine translated BRAFV600 stage IV melanoma Targeted therapy: “real world” data on encorafenib plus binimetinib The BERING-Melanoma multicenter study is monitoring the use of encorafenib with binimetinib in the first- and second-line setting* in patients with advanced BRAFV600-mutated malignant melanoma in everyday care in Germany, Austria,…
View Post 12 min This content is machine translated Axial spondyloarthritis and psoriatic arthritis Effective and efficient against pain The anti-IL-17A monoclonal antibody ixekizumab has already been approved since 2016 for the treatment of moderate to severe plaque psoriasis and psoriatic arthritis. In 2020, axial spondyloarthritis (axSpA) was added… CME-Test
View Post 7 min This content is machine translated Psoriasis in childhood and adolescence Secukinumab in juvenile plaque psoriasis – sustained efficacy demonstrated Treatment options for psoriasis patients in childhood and adolescence are much more limited compared to the treatment spectrum for adults. But pediatric patients can also benefit from targeted treatment. This…
View Post 6 min This content is machine translated Multiple Myeloma CAR-T cells, autologous and allogeneic stem cell transplantation: Who is winning the race? Autologous stem cell transplantation is highly valued in the treatment of multiple myeloma. In recent decades, the use of allogeneic blood stem cell transplantation has also been tested, but despite…
View Post 4 min This content is machine translated Rheumatoid arthritis Translational medicine and omics analyses: focus on proven and new therapeutic approaches In rheumatoid arthritis, the immune system attacks the synovial membrane of the synovium. If left untreated, there is a risk of gradual joint destruction. DMARDs are therefore used in severe…
View Post 2 min This content is machine translated Fixed combination of calcipotriol and betamethasone dipropionate Proactive therapy with spray foam for psoriasis vulgaris persistently effective Proactive management with the foam spray fixed combination of calcipotriol and betamethasone dipropionate resulted in fewer relapses and improved long-term symptom control compared with a reactive treatment strategy with a…
View Post 10 min This content is machine translated Prostate Cancer PSMA in diagnostics and therapy: Where is the journey leading? The prostate specific membrane antigen (PSMA) plays an increasingly important role not only in the diagnosis of prostate carcinoma. The radioligand 117Lutetium-PSMA-617also provides a new therapeutic option in advanced castration-resistant…
View Post 3 min This content is machine translated Depression Antidepressants: relapse prophylaxis for sustained therapeutic success For moderate to severe depressive episodes, the efficacy of treatment with antidepressants is considered proven. Remission-stabilizing maintenance therapy is an important aspect to reduce the risk of relapse. As a relapse…
View Post 10 min This content is machine translated Dementia Clarification in practice Questions about brain performance due to subjective complaints or environment-reported cognition problems are increasingly common in primary care consultations. This is due to demographic developments. Dementias increase with age: 75-… CME-Test
View Post 3 min This content is machine translated Special extract of peppermint and caraway oil Phytopreparation inhibits intestinal motility and promotes secretion An in vitro study on human digestive tissue published in 2021 demonstrated secretion-promoting effects in addition to the muscle-relaxing effects observed in previous studies. In addition, the scientists found that…
View Post 4 min This content is machine translated Chronic spontaneous urticaria When antihistamines are not enough – ligelizumab soon available in addition to omalizumab? The biologic omalizumab has empirically well-documented efficacy and safety and is considered the treatment of choice in international guidelines for cases of chronic spontaneous urticaria with inadequate response to antihistamines.…
