This content is machine translated Psoriatic arthritis (PsA) From an interdisciplinary perspective, what are the current “Unmet needs”? Psoriatic arthritis (PsA) manifests clinically as a heterogeneous disease with phenotypically highly variable expression. Most of those affected already suffer from skin psoriasis. Predicting which psoriasis patients are at increased risk…
View Post 4 min This content is machine translated Multiple sclerosis MS therapy: updated guideline and further updates at a glance The range of disease-modifying therapies (DMTs) for MS patients has expanded steadily in recent years. This has also been incorporated into the new edition of the DGN guideline. The benefits…
View Post 4 min This content is machine translated Generalized pustular psoriasis New study data on anti-IL-36 therapy Treatment options for generalized pustular psoriasis have been severely limited. Therefore, there is a high demand for new therapeutic options. Spesolimab is considered a promising hope. In a phase II…
View Post 2 min This content is machine translated RA in over 70s bDMARDs and JAK inhibitors with lower risk of infection compared to baseline therapy. In clinical practice, older rheumatoid arthritis patients tend to receive treatment with biologics (bDMARDs) less frequently than younger patients, although the use of conventional basic therapeutics is often not appropriate…
View Post 5 min This content is machine translated State-of-the-Art Obesity Therapy Combine lifestyle measures with drug treatment Obesity is on the rise worldwide and is one of the greatest public health challenges of our time. In addition to dietary changes and exercise, GLP-1 agonists are a new…
View Post 4 min This content is machine translated Modern treatment of type 2 diabetes Combine metformin with new substance classes at an early stage Lifestyle modification alone is usually not sufficient in type 2 diabetes. Metformin is still considered the first-line drug. However, SGED and international professional societies recommend early combination with an SGLT-2…
View Post 4 min This content is machine translated Axial spondyloarthritis The road to diagnosis is still far too long Inflammatory chronic back pain is an indication of possible axial spondyloarthritis. It is a major challenge for primary care physicians to identify those with axSpA among the many back pain…
View Post 11 min This content is machine translated Atopic dermatitis The role of the key cytokine IL-13 The Th2 response of atopic dermatitis is strongly controlled by IL-13, which activates the type II receptor by binding to the IL-13Rα chain. IL-13 is expressed at higher levels than… CME-Test
View Post 5 min This content is machine translated Biologics and JAK inhibitors New insights for RA therapy There are now four approved JAK inhibitors in Europe: tofacitinib, baricitinib, upadacitinib and filgotinib. While there has not been much news to report on the first two in the past…
View Post 4 min This content is machine translated Chronic spontaneous urticaria FcεRI as a potential biomarker for treatment response to omalizumab. In patients with chronic spontaneous urticaria, high baseline serum FcεRI levels may be a predictor of response to omalizumab treatment. This is the conclusion of a study presented at the…
View Post 6 min This content is machine translated The Parkinson therapy in the very old Age does not make it better Although old age is not typical for PD and there are also young patients, the disease has always been associated with elderly people. Sufferers also often have to contend with…
