This content is machine translated Metastatic colorectal cancer Comparison between bevacizumab and cetuximab in KRAS exon2 wild type. According to preliminary results of a large phase III trial presented at this year’s ASCO congress, bevacizumab and cetuximab (combined with FOLFOX or FOLFIRI) show similar efficacy in terms of…
View Post 2 min This content is machine translated Multiple sclerosis Not all basic therapeutics are equally effective In the treatment of multiple sclerosis, various therapeutic options such as immunomodulators, immunosuppressants and monoclonal antibodies are available, but it is largely unclear how their relative mode of action is…
View Post 5 min This content is machine translated Alzheimer's disease Additional benefit in combination with cholinesterase inhibitors? As life expectancy increases, so does the number of people living with Alzheimer’s disease. A cure for this disease remains impossible, but several drugs have proven efficacy in the area…
View Post 3 min This content is machine translated PARTNER study To what extent do diabetic patients with severe aortic valve stenosis benefit from TAVI? The PARTNER trial was the first randomized trial to demonstrate that TAVI (transcatheter aortic valve implantation) is a valid alternative to surgical aortic valve replacement in patients at high surgical…
View Post 4 min This content is machine translated Breast Cancer How should action be taken without accurate study results? What is the evidence for primary tumor and metastasis in breast carcinoma? Are there treatment options that will not harm the child if a pregnant woman is found to have…
View Post 2 min This content is machine translated HSP90 inhibition A new therapeutic approach for breast cancer In an initial phase II study in metastatic breast cancer, the HSP90 inhibitor ganetespib has shown promising antitumor activity in HER2-positive and triple-negative breast cancer (TNBC). Due to the favorable…
View Post 2 min This content is machine translated SAKK publication Cancer patients receive different regional treatment at the end of their lives A study co-led by the Swiss Association for Clinical Cancer Research (SAKK) and published in the journal BMC Cancer concludes that place of residence, insurance, age, and type of cancer…
View Post 2 min This content is machine translated Prostate Cancer HAROW Study Provides Fuel for Discussion A German health services research study (HAROW) is causing a stir: it raises the question of whether low-risk prostate cancer should be treated with surgery, radiation or (only) active surveillance.…
View Post 6 min This content is machine translated Arthroscopic knee surgery A process under the microscope Orthopaedic surgeons practicing arthroscopy are currently facing significant challenges. From the highest echelon of the journal Olympus, a series of randomized trials have suggested that no specific treatment effect can…
View Post 4 min This content is machine translated Phytotherapy for asthma and COPD Clinical studies show mixed results In various folk medicine traditions such as TCM, Ayurvedic or Indian medicine, there are a number of herbal preparations for asthma and COPD, but they have often not been verified…
View Post 3 min This content is machine translated Newly diagnosed multiple myeloma Does a proteasome inhibitor offer new therapeutic options? One study discussed at the ASH meeting involved a regimen consisting of oral MLN9708 administered twice weekly plus lenalidomide and dexamethasone in patients with newly diagnosed multiple myeloma. It concludes…
