This content is machine translated Non-steroidal anti-inflammatory drugs Do they protect against basal cell and squamous cell carcinomas? To date, there have been few epidemiologic studies examining the association between nonsteroidal anti-inflammatory drugs (NSAIDs) and fair skin cancer. However, since it is known that NSAIDs may well have…
View Post 4 min This content is machine translated Results from the ICE and SOFT studies Does capecitabine prove effective and who benefits from ovarian suppression? Two studies presented at the 2014 San Antonio Breast Cancer Symposium had been eagerly anticipated: ICE tested adjuvant monochemotherapy with capecitabine in an elderly patient population and SOFT tested ovarian…
View Post 4 min This content is machine translated Prevention and treatment of ER-positive breast cancer IBIS-1 update shows promising results At the San Antonio Breast Cancer Symposium, people discussed prevention options for women at high risk for breast cancer. Tamoxifen continues to show a significant reduction in the incidence of…
View Post 5 min This content is machine translated Pooled analysis of four studies Is a St. John’s wort extract better tolerated than SSRIs? This article is the German abstract of a study [1] published in the journal International Clinical Psychopharmacology. The authors pooled the compatibility data from four studies and evaluated them. They…
View Post 4 min This content is machine translated Malignant hematological diseases One tablet – no chemotherapy Will there soon be a once-daily tablet that will eliminate the need for chemotherapy for malignant hematologic diseases such as acute myeloid leukemia? This question is being investigated in an…
View Post 4 min This content is machine translated Mantle cell lymphoma First- and second-line lenalidomide Mantle cell lymphoma (MZL) is an aggressive non-Hodgkin’s lymphoma that accounts for approximately 3-6% of all NHL cases. It has a poor prognosis, especially after failure of first-line therapy. Lenalidomide…
View Post 2 min This content is machine translated Small papillary thyroid carcinomas Is active monitoring enough? There are some centers that advocate pursuing a strategy of active surveillance without surgery for small papillary thyroid carcinomas (PTC), which are increasingly encountered in clinical practice. A population-based cohort…
View Post 6 min This content is machine translated Highlights from the AHA Congress 2014 What insights did IMPROVE-IT and DAPT bring? The American Heart Association conference in Chicago drew attention primarily for two long-awaited study updates. At this point, the most important results from the IMPROVE-IT and DAPT studies will be…
View Post 3 min This content is machine translated News from the ASH Congress on Nivolumab High response rates even in pretreated Hodgkin’s lymphomas Preclinical studies show that Sternberg-Reed cells, characteristic of classical Hodgkin lymphoma, use the PD-1 pathway to evade immunodetection. Therefore, immune checkpoint inhibitors such as nivolumab, which binds to the PD-1…
View Post 2 min This content is machine translated Bladder Cancer Promising immunotherapy A new phase I trial with a compound targeting the immunosuppressive protein PDL1 shows promising results with a good toxicity profile. This provides a potentially new class of drugs for…
View Post 3 min This content is machine translated Transcatheter Aortic Valve Implantation (TAVI) PARTNER study shows survival benefit even after five years In September 2014, the Transcatheter Cardiovascular Therapeutics Conference was held in Washington, D.C., USA. Dr. Samir Kapadia, Cleveland Clinic, USA, presented the 5-year results of the PARTNER study on behalf…
