This content is machine translated HSP90 inhibition A new therapeutic approach for breast cancer In an initial phase II study in metastatic breast cancer, the HSP90 inhibitor ganetespib has shown promising antitumor activity in HER2-positive and triple-negative breast cancer (TNBC). Due to the favorable…
View Post 2 min This content is machine translated SAKK publication Cancer patients receive different regional treatment at the end of their lives A study co-led by the Swiss Association for Clinical Cancer Research (SAKK) and published in the journal BMC Cancer concludes that place of residence, insurance, age, and type of cancer…
View Post 2 min This content is machine translated Prostate Cancer HAROW Study Provides Fuel for Discussion A German health services research study (HAROW) is causing a stir: it raises the question of whether low-risk prostate cancer should be treated with surgery, radiation or (only) active surveillance.…
View Post 6 min This content is machine translated Arthroscopic knee surgery A process under the microscope Orthopaedic surgeons practicing arthroscopy are currently facing significant challenges. From the highest echelon of the journal Olympus, a series of randomized trials have suggested that no specific treatment effect can…
View Post 4 min This content is machine translated Phytotherapy for asthma and COPD Clinical studies show mixed results In various folk medicine traditions such as TCM, Ayurvedic or Indian medicine, there are a number of herbal preparations for asthma and COPD, but they have often not been verified…
View Post 3 min This content is machine translated Newly diagnosed multiple myeloma Does a proteasome inhibitor offer new therapeutic options? One study discussed at the ASH meeting involved a regimen consisting of oral MLN9708 administered twice weekly plus lenalidomide and dexamethasone in patients with newly diagnosed multiple myeloma. It concludes…
View Post 4 min This content is machine translated 1st Swiss Symposium Peritoneal Malignancies and HIPEC Enabling individualized treatment At the first Swiss symposium on peritoneal malignancies and HIPEC in St. Gallen, experts spoke on the topics of ovarian cancer and metastatic colorectal cancer. It was about current and…
View Post 6 min This content is machine translated Non-Hodgkin's lymphoma and myelodysplastic syndrome What are the benefits of lenalidomide and pomalidomide? At the ASH Congress in New Orleans, the focus was on the efficacy and safety of lenalidomide plus low-dose dexamethasone in the treatment of patients with newly diagnosed multiple myeloma.…
View Post 4 min This content is machine translated Mistletoe Findings on efficacy from cohort studies The randomized, placebo-controlled trial has become the gold standard of medical research today. This development has been accompanied by an ever-increasing emphasis on evidence-based medicine in curricula and guidelines, increasing…
View Post 7 min This content is machine translated Cardiology Highlights 2013 New practice-relevant European guidelines What news did the 2013 European Congress of Cardiology in Amsterdam bring? Discussed were not only practice-relevant guidelines, but also the current trends regarding lifestyle modifications. Furthermore, studies on the…
View Post 3 min This content is machine translated St. John's wort in depression therapy Health services research complements double-blind studies Depression is very common among mental illnesses. Unipolar depression is the third leading cause of so-called Disability Adjusted Life Years (DALY), years of life associated with health limitations and disability.…