This content is machine translated Mantle cell lymphoma First- and second-line lenalidomide Mantle cell lymphoma (MZL) is an aggressive non-Hodgkin’s lymphoma that accounts for approximately 3-6% of all NHL cases. It has a poor prognosis, especially after failure of first-line therapy. Lenalidomide…
View Post 2 min This content is machine translated Small papillary thyroid carcinomas Is active monitoring enough? There are some centers that advocate pursuing a strategy of active surveillance without surgery for small papillary thyroid carcinomas (PTC), which are increasingly encountered in clinical practice. A population-based cohort…
View Post 6 min This content is machine translated Highlights from the AHA Congress 2014 What insights did IMPROVE-IT and DAPT bring? The American Heart Association conference in Chicago drew attention primarily for two long-awaited study updates. At this point, the most important results from the IMPROVE-IT and DAPT studies will be…
View Post 3 min This content is machine translated News from the ASH Congress on Nivolumab High response rates even in pretreated Hodgkin’s lymphomas Preclinical studies show that Sternberg-Reed cells, characteristic of classical Hodgkin lymphoma, use the PD-1 pathway to evade immunodetection. Therefore, immune checkpoint inhibitors such as nivolumab, which binds to the PD-1…
View Post 2 min This content is machine translated Bladder Cancer Promising immunotherapy A new phase I trial with a compound targeting the immunosuppressive protein PDL1 shows promising results with a good toxicity profile. This provides a potentially new class of drugs for…
View Post 3 min This content is machine translated Transcatheter Aortic Valve Implantation (TAVI) PARTNER study shows survival benefit even after five years In September 2014, the Transcatheter Cardiovascular Therapeutics Conference was held in Washington, D.C., USA. Dr. Samir Kapadia, Cleveland Clinic, USA, presented the 5-year results of the PARTNER study on behalf…
View Post 5 min This content is machine translated 19th Zurich Cardiovascular Day Brain stroke – a clinical picture from two different perspectives Two experts from different fields spoke on the topic of “cerebral stroke” at the 19th Zurich Cardiovascular Day. From a neurological perspective, cerebral microbleeds have been identified as a risk…
View Post 2 min This content is machine translated Personalized vaccination Each patient gets his own medicine Advances in so-called cancer vaccines were discussed at the ESMO Symposium on Immuno-oncology in Geneva. In the most elaborate study to date on this topic, researchers are currently investigating the…
View Post 2 min This content is machine translated Research result at the University of Bern An alternative to antibiotics? An international team of researchers led by Bern has developed a new substance to treat severe bacterial infections – without the use of antibiotics. This could also prevent antibiotic resistance…
View Post 2 min This content is machine translated Cancer risk with contraception with IUD Neither baby nor cancer Recently, evidence has accumulated in the literature that intrauterine devices may reduce the risk of developing endometrial cancer. What is the current study situation on this? This question was explored…
View Post 7 min This content is machine translated European Diabetes Congress in Vienna High expectations for new therapeutic options At the EASD congress in Vienna, gliptins, gliflozines and further improved insulins were seen as the great hope in diabetology. But medical technology also presented itself in a good position;…
