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Studies

2489 posts
  • This content is machine translated Parkinson's disease and movement disorders

Narcolepsy, biomarkers, and dystonia in light of new evidence.

The International Parkinson and Movement Disorder Society (MDS) gathers thousands of clinicians, researchers, trainees and industry advocates with an interest in current research and approaches to the diagnosis and treatment…
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  • 6 min
  • This content is machine translated Melanoma in advanced stages

Treatment strategies in the adjuvant and neoadjuvant setting

The introduction of checkpoint inhibitors and targeted therapy with kinase inhibitors revolutionized the treatment options for patients with advanced-stage melanoma. While there is already a lot of evidence for immunotherapy…
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  • 8 min
  • This content is machine translated "Treat-to-Target" or "High Intensity".

Which statin strategy is better?

Titrated individually according to LDL target value (“Treat to Target”) or uniformly high doses for all patients (“High Intensity”)? Which of the two strategies is clinically better in the case…
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  • 11 min
  • This content is machine translated Osteoporosis

New in diagnostics and therapy

Since 2018, the update of the S3 guideline Prophylaxis, Diagnosis and Therapy of Osteoporosis (AWMF 183-001) took place after previous update of the underlying PICO questions (Population-Intervention-Comparison-Outcome questions) for systematic…
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  • 2 min
  • This content is machine translated Human Biomonitoring

First results of pilot phase provides representative data

In Switzerland, there are several studies that include human biomonitoring. However, these do not yet provide data representative of Switzerland, so a national study is being considered. Now the first…
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  • 12 min
  • This content is machine translated Palliative care symptom and needs assessment.

What screening tools are helpful?

In view of the new and mostly well-tolerated therapies, the palliative life and treatment time of oncological patients is increasingly extended. It is a major challenge to identify patients in…
CME-Test
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  • 4 min
  • This content is machine translated Heart failure: ESC guideline update 2023

Treatment of HFmrEF – what’s new?

The European Society of Cardiology (ESC) recently updated its guidelines. Consequently, based on the EMPEROR-Preserved and DELIVER trials, the use of SGLT-2 inhibitors is now recommended for all stages of…
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  • 3 min
  • This content is machine translated Study Report

Dupilumab in 6- to 11-year-old AD patients: Effects on skin barrier function

Atopic dermatitis (AD) is one of the most common diseases in childhood and adolescence. An observational study evaluated the effects of dupilumab in a subpopulation of 6–11-year-old patients with moderate-to-severe…
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  • 6 min
  • This content is machine translated Moderate depressive disorder

Post hoc analysis of a comparative study – Hypericum as an effective antidepressant.

Numerous studies show that medicines based on St. John’s wort (Hypericum perforatum) are effective against depressive mood. The evidence base includes not only placebo comparisons, but also reference-controlled comparative studies.…
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  • 7 min
  • This content is machine translated Heart failure

International validation of the MECKI score

Current European guidelines for the management of heart failure recommend the use of risk scores. Among these, the MECKI score (Metabolic Exercise Test Data Combined with Cardiac and Kidney Indexes)…
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  • 15 min
  • This content is machine translated Hidradenitis suppurativa

Etiopathogenesis, diagnosis and treatment – an update

The pathogenesis of hidradenitis suppurativa (HS) has not yet been fully clarified; it is assumed that there are multifactorial interactions. The most important risk factors and comorbidities include smoking, obesity…
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