This content is machine translated Hypertrophic cardiomyopathies (HCM) How do myosin inhibitors perform in different HCM phenotypes? Cardiac myosin inhibitors have been developed as a targeted therapeutic option for modulating sarcomere function. While in clinical trials in obstructive hypertrophic cardiomyopathy they brought about a greater improvement in...…
View Post 6 min This content is machine translated Results of the FOREST HCM study Symptomatic obstructive hypertrophic cardiomyopathy Myosin inhibition is considered a key therapeutic approach in the treatment of obstructive hypertrophic cardiomyopathy (oHCM). In addition to mavacamten, aficamten is now being clinically investigated as a potentially short-acting,...…
