This content is machine translated Severe asthma Anti-IL-5/-5Rα biologics impress in the real world Three biologics targeting interleukin 5 (IL-5) or its receptor (IL-5Rα) are approved for use in patients with severe asthma. In a meta-analysis, Greek scientists have now investigated the clinical response...…
View Post 5 min This content is machine translated Bronchiectasis and Pseudomonas aeruginosa infection Statistically significant reduction in the frequency of exacerbations A chronic lung infection with Pseudomonas aeruginosa is associated with an increased exacerbation and mortality rate in people affected by bronchiectasis. Inhaled antibiotics are frequently used in clinical practice to...…
View Post 6 min This content is machine translated Gender differences in asthma Men have it better again It is known that the clinical picture of asthma can vary depending on gender. However, how exactly this affects the severity of symptoms, the function of large and small airways,…
View Post 5 min This content is machine translated RSV-related COPD exacerbations Combination of test methods could increase diagnosis rate Respiratory syncytial virus (RSV) is increasingly recognized as a major pathogen in frail older adults and a cause of exacerbations of chronic obstructive pulmonary disease (COPD). Although there are studies...…
View Post 5 min This content is machine translated COPD and CVD in PRISm patients Exacerbations damage the lungs – and the heart COPD exacerbations not only contribute to the progression of lung disease, but can also increase the risk of cardiovascular disease (CVD). An American research group investigated the relationship between COPD…
View Post 4 min This content is machine translated Dupilumab for COPD and asthma Exacerbations reduced and lung function improved The monoclonal antibody dupilumab blocks the common receptor component for interleukin (IL)-4 and IL-13, the central drivers of type 2 inflammation. It has been approved in Switzerland since 2019, and…
View Post 6 min This content is machine translated COPD Which patients benefit from ICS as an add-on? The eosinophil count in the blood (EOS) is considered a suitable biomarker for deciding whether COPD patients are likely to derive additional clinical benefit from inhaled steroids (ICS) as an…
View Post 5 min This content is machine translated Vaccines against pneumococci, influenza & RSV Avoid exacerbations with the vaccination Infectious diseases play a central role in exacerbations of chronic respiratory diseases and are also responsible for the progression of the disease.of the underlying disease. For many important pathogensof the…
View Post 5 min This content is machine translated COPD: Update for the primary care physician Counteract exacerbations and improve quality of life To achieve a reduction in the frequency of exacerbations – a primary therapeutic goal in COPD – a multimodal therapy concept is recommended. Regarding bronchodilator inhalation therapy, SABA and SAMA…
View Post 3 min This content is machine translated Severe asthma A switch can be worthwhile – most of the time A proportion of patients with severe eosinophilic bronchial asthma show inadequate effects under IL-5 antibody therapy. Switching to an IL-5 receptor antibody may promise success under certain conditions. A recent…
View Post 6 min This content is machine translated COPD therapy Biomarkers could facilitate many things 22-40% of all COPD patients experience at least one moderate or severe exacerbation annually. Patients with frequent exacerbations have a worse prognosis. A team of researchers has been looking at…
